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Nirmatrelvir/ritonavir for COVID-19 in children passes safety test
Treatment of symptomatic COVID-19 with nirmatrelvir/ritonavir in children at least 6 years of age who are at risk of progression to severe disease appears to be safe and well-tolerated, with pharmacokinetic data from the open-label phase 2/3 EPIC-Peds* study indicating suitable dosing regimens for two distinct weight categories of this population.
ARBs a good alternative to ACEIs in patients with acute MI
The incidence of death is comparable between patients with acute myocardial infarction (MI) without heart failure (HF) receiving angiotensin II receptor blockers (ARBs) and those taking angiotensin-converting enzyme inhibitors (ACEIs), a study has shown.
Trastuzumab deruxtecan improves PFS in metastatic breast cancer, but ups ILD risk
Treatment with trastuzumab deruxtecan (T-DXd) demonstrates efficacy in patients with metastatic hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2–) breast cancer but may result in adverse events, such as interstitial lung disease (ILD), suggests a study.
Sacituzumab govitecan improves survival in advanced breast cancer
Treatment with sacituzumab govitecan (SG), a novel antibody-drug conjugate, provides survival benefits in women diagnosed with hormone receptor-positive/human epidermal growth factor receptor 2-negative (HR+/HER2–) breast cancer, reports a study.
