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NAFLD may cause sexual dysfunction in premenopausal women

16 Sep 2024

The presence of nonalcoholic fatty liver disease (NAFLD) can impair the sexual function of premenopausal women, suggests a study in Egypt.

NAFLD may cause sexual dysfunction in premenopausal women

16 Sep 2024

HELIOS-B shines on vutrisiran for ATTR-CM

16 Sep 2024 by

In the phase III HELIOS-B trial, vutrisiran reduced death and cardiovascular (CV) events in patients with transthyretin amyloidosis with cardiomyopathy (ATTR-CM).

HELIOS-B shines on vutrisiran for ATTR-CM

16 Sep 2024

Aspirin may protect against pancreatic cancer

16 Sep 2024

Use of aspirin appears to be beneficial in the prevention of pancreatic cancer, according to a study.

Aspirin may protect against pancreatic cancer

16 Sep 2024

Bivalent RSV vaccine effective with favourable safety profile in infants through maternal immunization

16 Sep 2024

Respiratory syncytial virus (RSV) infection is a common cause of acute lower respiratory tract disease (LRTD) and a leading cause of hospitalization in infants. In Hong Kong, the single-dose RSV prefusion F protein–based (RSVpreF) vaccine, indicated for active immunization of pregnant individuals at a gestational age of 32–36 weeks, is now available for prevention of LRTD and severe LRTD caused by RSV in infants ≤6 months of age. This article discusses the burden of RSV infections and the efficacy and safety of the RSVpreF vaccine specifically against medically attended severe RSV-associated LRTD in infants, which demonstrated an efficacy of 81.8 percent at 90 days after birth and 69.4 percent at 180 days after birth in a pivotal trial.

Bivalent RSV vaccine effective with favourable safety profile in infants through maternal immunization

16 Sep 2024

Bivalent RSVpreF vaccine confers durable protection against RSV-associated LRTD in older individuals

16 Sep 2024

Respiratory syncytial virus (RSV) is an important cause of severe respiratory illness, often leading to hospitalization and/or death in older individuals. A bivalent (RSV A and RSV B) RSV prefusion F protein–based (RSVpreF) vaccine is now available in Hong Kong for prevention of lower respiratory tract disease (LRTD) caused by RSV in individuals ≥60 years of age. This article highlights the single-dose vaccine’s sustained protective efficacy through two full RSV seasons, with cumulative vaccine efficacy against RSV-associated LRTD with ≥3 signs or symptoms exceeding 80 percent.

Bivalent RSVpreF vaccine confers durable protection against RSV-associated LRTD in older individuals

16 Sep 2024

Adjunctive metformin offers no protection against pre-eclampsia

15 Sep 2024

Among pregnant women with early gestational diabetes or pre-existing type 2 diabetes (T2D), using metformin in addition to insulin neither lowers the likelihood of preterm pre-eclampsia nor improves serum biomarkers associated with cardiovascular disease risk, according to a study.

Adjunctive metformin offers no protection against pre-eclampsia

15 Sep 2024

No benefit to SGLT2 inhibitor therapy in hospitalized COVID-19 patients

15 Sep 2024 by

Adding sodium–glucose co-transporter-2 (SGLT2) inhibitors to usual care in the treatment of hospitalized patients with COVID-19 does not necessarily lead to improved survival, according to the results of a meta-analysis.

No benefit to SGLT2 inhibitor therapy in hospitalized COVID-19 patients

15 Sep 2024

Enzalutamide edges out abiraterone in mCRPC

15 Sep 2024 by

In the treatment of patients with metastatic castration-resistant prostate cancer (mCRPC), the use of enzalutamide yields small improvements in outcomes when compared with abiraterone acetate, according to a retrospective study.

Enzalutamide edges out abiraterone in mCRPC

15 Sep 2024

NOACs better than VKAs at preventing deaths, CVD in AF patients with or without impaired kidney

15 Sep 2024 by

For atrial fibrillation (AF) patients with normal or impaired renal function, use of nonvitamin K antagonist oral anticoagulants (NOACs) results in improved outcomes relative to vitamin K antagonist (VKA) therapy, suggests a study presented at ESC 2024.

NOACs better than VKAs at preventing deaths, CVD in AF patients with or without impaired kidney

15 Sep 2024

Menopausal hormone therapy may boost beneficial bacteria in vaginal microbial community

15 Sep 2024

Postmenopausal women who use menopausal hormone therapy (MHT) appear to have increased Lactobacillus abundance and lower vaginal microbial community diversity, according to a study.

Menopausal hormone therapy may boost beneficial bacteria in vaginal microbial community

15 Sep 2024

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NAFLD may cause sexual dysfunction in premenopausal women

NAFLD may cause sexual dysfunction in premenopausal women

HELIOS-B shines on vutrisiran for ATTR-CM

HELIOS-B shines on vutrisiran for ATTR-CM

Aspirin may protect against pancreatic cancer

Aspirin may protect against pancreatic cancer

Bivalent RSV vaccine effective with favourable safety profile in infants through maternal immunization

Bivalent RSV vaccine effective with favourable safety profile in infants through maternal immunization

Bivalent RSVpreF vaccine confers durable protection against RSV-associated LRTD in older individuals

Bivalent RSVpreF vaccine confers durable protection against RSV-associated LRTD in older individuals

Adjunctive metformin offers no protection against pre-eclampsia

Adjunctive metformin offers no protection against pre-eclampsia

No benefit to SGLT2 inhibitor therapy in hospitalized COVID-19 patients

No benefit to SGLT2 inhibitor therapy in hospitalized COVID-19 patients

Enzalutamide edges out abiraterone in mCRPC

Enzalutamide edges out abiraterone in mCRPC

NOACs better than VKAs at preventing deaths, CVD in AF patients with or without impaired kidney

NOACs better than VKAs at preventing deaths, CVD in AF patients with or without impaired kidney

Menopausal hormone therapy may boost beneficial bacteria in vaginal microbial community

Menopausal hormone therapy may boost beneficial bacteria in vaginal microbial community