News & Updates

Treatment with depemokimab results in a substantial decrease in exacerbations, with an acceptable safety profile, among severe asthma patients with an eosinophilic phenotype, results of the SWIFT-1 and 2 studies have shown.

The time of steroids as the treatment of choice for asthma and chronic obstructive pulmonary disease (COPD) exacerbations appears to be nearing its end with the arrival of a new monoclonal antibody therapy, according to the results of the ABRA study.

COVID-19 variants delta and omicron BA.1 or BA.2 do not pose a substantial threat of long-term autoimmune complications, except for a modest elevation in inflammatory bowel disease and bullous skin disorders among hospitalized patients during the omicron predominance in Singapore, as shown in a study.

In a nationwide French cohort study, myocarditis attributed to COVID-19 mRNA vaccination causes fewer cardiovascular (CV) events at 18 months of follow-up than that attributed to SARS-CoV-2 infection or myocarditis of conventional aetiologies.

The introduction of targeted biologic therapies has revolutionized the management of severe asthma, where clinical remission is now viewed as a realistic treatment goal. In an interview with MIMS Doctor, Professor Ken Ka-Pang Chan of the Department of Medicine and Therapeutics, the Chinese University of Hong Kong, discussed updates in the Global Initiative for Asthma (GINA) 2024 Report that reflect recent research findings on clinical remission with biologic therapy. He further highlighted how tezepelumab, a first-in-class monoclonal antibody that targets thymic stromal lymphopoietin (TSLP), may help achieve this goal through its broad action on multiple downstream inflammatory pathways involved in asthma pathophysiology.