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How viable is a self-administered injection in adults with HIV?
A substudy of the phase III FLAIR study has found comparable efficacy and pharmacokinetics for cabotegravir (CAB) plus rilpivirine (RPV) via subcutaneous (SC) administration relative to those via intramuscular (IM) gluteal injections among virally suppressed individuals living with HIV-1.
How viable is a self-administered injection in adults with HIV?
05 Aug 2024
KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer
Perioperative pembrolizumab plus chemotherapy confers survival benefit in individuals with locally advanced gastric and gastroesophageal junction (G/GEJ) cancer in the final analysis of the phase III KEYNOTE-585 trial.
KEYNOTE-585 final analysis support perioperative pembrolizumab-chemo for G/GEJ cancer
05 Aug 2024
1-year mortality elevated after procedural/spontaneous myocardial infarction
A significantly higher 1-year mortality is seen following procedural myocardial infarction (pMI) and spontaneous MI (spMI) with troponin peak >35x the upper reference level (URL), reports a study. On the other hand, only spMI demonstrates a significant influence on mortality for troponin levels ≤35x.