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INHALE-3 underpins alternate insulin delivery method for T1D

17 Jul 2024 by

Findings from the phase IV INHALE-3 trial support inhaled insulin for the management of type 1 diabetes (T1D) in adults, underlining its role as an alternative insulin solution to enhance diabetes management.

INHALE-3 underpins alternate insulin delivery method for T1D

17 Jul 2024

Targeting IL-5 in hypereosinophilic diseases: From bench to bedside

17 Jul 2024 by

Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare eosinophilic autoimmune disease that affects multiple organs. The lack of disease awareness and heterogeneous nature of clinical manifestations have made diagnosis and management of EGPA challenging. At Advances in Medicine (AIM) 2024, Professor Hiromichi Tamaki, a rheumatologist from St. Luke’s International Hospital in Japan, discussed how EGPA is diagnosed, presented real-world evidence on mepolizumab (an anti–interleukin [IL]-5 therapy) in EGPA and illustrated mepolizumab’s clinical benefits through several patient cases.

Targeting IL-5 in hypereosinophilic diseases: From bench to bedside

17 Jul 2024

Anti-TSLP treatment may extend care to a broad range of severe asthma patients

17 Jul 2024 by

Inhibition of thymic stromal lymphopoietin (TSLP), a crucial epithelial cytokine with broad effects on airway inflammation, has emerged as a potential therapeutic approach for severe asthma. At an industry-sponsored symposium during Autumn Respiratory Seminar (ARS) 2023 jointly organized by the Hong Kong Thoracic Society and the CHEST Delegation Hong Kong and Macau, Dr Hassan Burhan of the Royal Liverpool University Hospital, Liverpool, UK, discussed the role of epithelial cytokines in inflammation and airway hyperresponsiveness (AHR), and reviewed the clinical evidence supporting the use of tezepelumab, an anti-TSLP monoclonal antibody (mAb), among patients with severe asthma of diverse phenotypes. He also shared a case illustrating tezepelumab use in severe uncontrolled asthma (SUA).

Anti-TSLP treatment may extend care to a broad range of severe asthma patients

17 Jul 2024

$Bisphosphonates cut fracture risk in older cirrhosis patients$

Bisphosphonates cut fracture risk in older cirrhosis patients

17 Jul 2024

Older patients with cirrhosis who are taking bisphosphonates appear to have a reduced incidence of fractures overall, according to a study.

Bisphosphonates cut fracture risk in older cirrhosis patients

17 Jul 2024

Red light therapy for eyesight improvement: A short overview

17 Jul 2024 by

Red light therapy, sometimes referred to as photobiomodulation therapy or PBMT, has garnered significant interest because of its possible medical advantages, especially in the field of ophthalmology. Low-power red to near-infrared (NIR) light is used in PBMT to activate biological processes.

Red light therapy for eyesight improvement: A short overview

17 Jul 2024

Novel HRS9531 shows promise as treatment for obesity in Chinese adults

17 Jul 2024 by

Once-weekly treatment with HRS9531, a novel dual GLP-1* and GIP** receptor agonist, resulted in substantial reductions in body weight among Chinese patients with obesity, according to a study presented at ADA 2024.

Novel HRS9531 shows promise as treatment for obesity in Chinese adults

17 Jul 2024

Original New Drug Application Approvals by US FDA (1-15 July 2024)

17 Jul 2024

New drug applications approved by US FDA as of 1-15 July 2024 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (1-15 July 2024)

17 Jul 2024

Automated insulin delivery system beneficial for T2D management

16 Jul 2024 by

An automated insulin delivery (AID) system appears to improve clinical outcomes in people with type 2 diabetes (T2D), with the pivotal SECURE-T2D trial showing substantial improvements in glycated haemoglobin, total daily insulin dose, and diabetes distress, without increasing the risk of hypoglycaemia.

Automated insulin delivery system beneficial for T2D management

16 Jul 2024

Breastfeeding may prevent development of JSpA in infants

16 Jul 2024

Infant factors affecting the microbiome appears to influence the occurrence of juvenile spondyloarthritis (JSpA), suggests a study, noting a link between exclusive breastfeeding and lower odds of JSpA.

Breastfeeding may prevent development of JSpA in infants

16 Jul 2024

Eating more fibre-rich foods, less red meat and sugar may prolong life expectancy

16 Jul 2024 by

Changing your usual eating pattern to one that is focused on longevity can bring substantial increases in life expectancy (LE), suggests a study that involved seven countries. These dietary changes include more whole grains, legumes, and nuts and less red/processed meats, sugars, and sugar-sweetened beverages.

Eating more fibre-rich foods, less red meat and sugar may prolong life expectancy

16 Jul 2024

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INHALE-3 underpins alternate insulin delivery method for T1D

INHALE-3 underpins alternate insulin delivery method for T1D

Targeting IL-5 in hypereosinophilic diseases: From bench to bedside

Targeting IL-5 in hypereosinophilic diseases: From bench to bedside

Anti-TSLP treatment may extend care to a broad range of severe asthma patients

Anti-TSLP treatment may extend care to a broad range of severe asthma patients

Bisphosphonates cut fracture risk in older cirrhosis patients

Bisphosphonates cut fracture risk in older cirrhosis patients

Red light therapy for eyesight improvement: A short overview

Red light therapy for eyesight improvement: A short overview

Novel HRS9531 shows promise as treatment for obesity in Chinese adults

Novel HRS9531 shows promise as treatment for obesity in Chinese adults

Original New Drug Application Approvals by US FDA (1-15 July 2024)

Original New Drug Application Approvals by US FDA (1-15 July 2024)

Automated insulin delivery system beneficial for T2D management

Automated insulin delivery system beneficial for T2D management

Breastfeeding may prevent development of JSpA in infants

Breastfeeding may prevent development of JSpA in infants

Eating more fibre-rich foods, less red meat and sugar may prolong life expectancy

Eating more fibre-rich foods, less red meat and sugar may prolong life expectancy