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Pioglitazone boosts HbA1c decrease while preventing ketone increase
In patients with type 1 diabetes (T1D) treated with SGLT2 inhibitors, such as dapagliflozin, the addition of pioglitazone helps to intensify the reduction in HbA1c and blocks the increase in plasma ketone driven by SGLT2 inhibitors, reports a study presented at ADA 2024. This enables long-term cardiovascular and renal outcome studies to be safely performed in T1D patients.
Pioglitazone boosts HbA1c decrease while preventing ketone increase
29 Jun 2024
Does lung biopsy worsen lung function, survival in IPF patients?
Surgical lung biopsy (SLB) neither reduces lung function nor increases the risk of death or lung transplantation in patients with idiopathic pulmonary fibrosis (IPF), reports a study.
Does lung biopsy worsen lung function, survival in IPF patients?
28 Jun 2024
Antibiotics may promote development of Kawasaki disease
Use of antibiotics appears to increase the risk of Kawasaki disease (KD) in children, reveals a study. KD development is potentially driven by gut microbiota changes due to antibiotic use.
Antibiotics may promote development of Kawasaki disease
28 Jun 2024
KRYSTAL-12 boosts adagrasib as 2L Tx alternative for KRASG12C-mutated NSCLC
Findings from the phase III KRYSTAL-12 trial underpin the treatment potential of adagrasib for previously treated metastatic non-small cell lung cancer (NSCLC) harbouring a KRASG12C mutation.