News & Updates

Patients with inflammatory bowel disease (IBD) who use statins appear to have a substantially reduced risk of primary sclerosing cholangitis (PSC), as shown in a retrospective study.

The intermittent 48-h “gap” schedule of olaparib in combination with carboplatin/paclitaxel and anthracycline chemotherapy provides substantial survival benefits in patients with germline BRCA-mutated breast cancer (gBRCA) regardless of their pathological complete response (pCR) status, results of the PARTNER trial have shown.

A handheld, 6-lead electrocardiographic (ECG) device may be an effective triage test that could reduce the need for 12-lead ECG monitoring in resource-limited, rifampin-resistant tuberculosis (RR-TB) treatment settings, according to a diagnostic prospective cohort study.

Adding the PD-1/CTLA-4 bispecific antibody cadonilimab to chemotherapy improves overall survival (OS) and progression-free survival (PFS) in individuals with untreated, HER2-negative, locally advanced or metastatic gastric or gastroesophageal junction (G/GEJ) cancer, including patients with PD-L1–low tumours, according to the interim results of the phase III COMPASSION-15 trial.

Lifestyle interventions, including increased fibre intake, have been shown to be effective in management of metabolic diseases. At a meeting coordinated by the Hong Kong College of Family Physicians (HKCFP), Dr Elaine Chow of the Department of Medicine & Therapeutics, the Chinese University of Hong Kong, described different types of dietary fibre and their various benefits, and shared clinical evidence on the role of psyllium fibre in minimizing cardiometabolic risk factors, such as elevated LDL-cholesterol (LDL-C), blood glucose levels and obesity.