News & Updates

In Singapore, poorly controlled gout appears to be common among men, Malays, and individuals with congestive cardiac failure, as reported in a study.

Use of undiluted lacosamide and levetiracetam to prevent seizures does not result in significant adverse events when administered via intravenous (IV) push over 5 min, according to a study. This approach appears to be a safe alternative form of administration to intermittent infusion.

Exposure to acid-suppressive therapy during the first year of life appear to come with a small but significant increase in the risk of fractures, according to a study.

Exposure to per- and polyfluoroalkyl substances (PFAS), dubbed “forever chemicals,” may contribute to a delay in puberty through its effects on body mass index (BMI) and sex hormones, as shown in a study.

The selective small molecule inhibitor of lipoprotein(a) (Lp[a]) formation muvalaplin helps reduce Lp(a) levels by up to 65 percent without safety and tolerability signals, as shown in the results of a phase I trial.

Treatment with 5-methyltetrahydrofolate (5-MTHF) significantly enhances the effect of propranolol in reducing hepatic venous pressure gradient (HVPG) in patients with cirrhosis and portal hypertension, a recent study has shown.

Individuals with ranitidine exposure do not appear to be at increased risk of cancer compared with those who have exposure to other histamine-2 receptor antagonists (H2RAs), according to a study.

First-line treatment with dabrafenib plus trametinib significantly increased overall response rate (ORR) in paediatric patients with low-grade glioma harbouring BRAF V600 mutations compared with standard chemotherapy, according to a recent study.