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Immune-mediated reactions predict survival in nivolumab-treated NSCLC patients
Several patients with nonsmall cell lung cancer (NSCLC) treated with nivolumab report developing immune-related adverse events (irAEs), primarily affecting the skin, lungs, and gastrointestinal system, according to a study.

Counselling, pamphlets boost flu vaccine intake in SG
Use of educational pamphlets alone and individualized counselling (IC) both lead to improved uptake of influenza vaccination, reports a Singapore study, noting that IC is not superior to pamphlets alone in increasing uptake.

GLP-1 agonists induce weight loss in diabetic patients with obesity
Initiation of a glucagon-like peptide-1 (GLP-1) agonist at standard glycaemic control doses may result in modest weight loss through 72 weeks in patients with overweight or obesity and type 2 diabetes, suggest the results of a real-world study.

Hydrochlorothiazide–lisinopril combo bests nifedipine for BP control in postpartum hypertension
In women with postpartum hypertension, treatment with combined hydrochlorothiazide (HCTZ)/lisinopril yields greater blood pressure (BP)-lowering benefit than nifedipine monotherapy, according to the results of a pilot study.

FTD/TPI-bevacizumab combo a new SoC for metastatic CRC?
A combination of trifluridine/tipiracil (FTD/TPI) and bevacizumab provided significant survival benefit when used as third-line treatment for refractory metastatic colorectal cancer (CRC) than FTD/TPI alone, findings from the phase III SUNLIGHT study suggest.

Prophylactic aflibercept reduces vision-threatening complications without gains in visual acuity
Treatment with intravitreal aflibercept in patients with nonproliferative diabetic retinopathy but without centre-involved diabetic macular edema appears to slow disease progression and reduce the risk of developing vision-threatening complications but fall short of improving visual acuity, according to a study.



