News & Updates

Exposure to the Janus kinase (JAK) inhibitors tofacitinib and upadacitinib, as well as to JAK inhibitors as a class, appears to put individuals at increased risk of developing herpes zoster infection, with the risk increasing at higher doses, as reported in a study.

A study in Singapore has found 75-percent inaccuracy in drug allergy labels among patients, indicating the importance of drug allergy evaluation in verifying these labels.

Inpatients normally use analgesics for pain, with comparable rates between those with and without cirrhosis, according to a recent study. Patients with cirrhosis, especially decompensated ones, are less likely to use acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) and more likely to use opioid analgesics.

Intravenous (IV) sodium acetate is as efficacious and safe as IV sodium bicarbonate for urine alkalinization with high-dose methotrexate (MTX) and may be used as a substitute in case of shortage, suggests a retrospective study.

Trough levels of infliximab are not predictive of the risk of short-term infectious (IC) or noninfectious complications (NIC) in adult patients with Crohn’s disease (CD), reports a study.

Treatment with corticosteroid in patients with drug-induced liver injury (DILI) does not appear to contribute to increased risk of death but rather helps normalize liver enzymes, as shown in a study.

Viral prophylaxis with valacyclovir 1 g three times daily following allogeneic haematopoietic cell transplantation (HCT) results in a lower incidence of clinically significant cytomegalovirus (CMV) infection as compared with acyclovir, according to a study.