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Does COVID-19 vaccine effectiveness wane over time?

26 Nov 2021 by

A large study conducted in Israel has suggested that the effectiveness of the BNT162b2 vaccine against COVID-19 decreases over time.

Does COVID-19 vaccine effectiveness wane over time?

26 Nov 2021

Community pharmacist intervention helps improve medication adherence

26 Nov 2021

A recent collaborative effort has successfully implemented a community pharmacist-led adherence intervention in several independent pharmacies in Buffalo, New York in the US, which has resulted in increased interactions with patients and, in some cases, improved adherence measures, reports a study.

Community pharmacist intervention helps improve medication adherence

26 Nov 2021

Methylprednisolone improves major kidney outcomes in patients with IgAN

26 Nov 2021 by

Treatment with methylprednisolone reduces the risk of kidney composite outcomes, including kidney failure, 40 percent decline in eGFR, or death due to kidney disease, in patients with IgA nephropathy (IgAN), according to the TESTING* study presented at ASN Kidney Week 2021.

Methylprednisolone improves major kidney outcomes in patients with IgAN

26 Nov 2021

6-month single antiplatelet regimen after DAPT post-PCI may reduce GI injury

25 Nov 2021 by

Among patients who received 6 months of dual antiplatelet therapy (DAPT) following percutaneous coronary intervention (PCI), switching to a single antiplatelet therapy (SAPT) regimen for another 6 months resulted in less gastrointestinal (GI) injury than continuing DAPT, results of the OPT-PEACE trial showed.

6-month single antiplatelet regimen after DAPT post-PCI may reduce GI injury

25 Nov 2021

Antihistamine raises appetite in adults

25 Nov 2021

Cyproheptadine appears to induce hunger in adults with poor appetite, as shown in a study.

Antihistamine raises appetite in adults

25 Nov 2021

Lumasiran reduces plasma oxalate in advanced PH1

25 Nov 2021 by

Treatment with the RNAi therapeutic lumasiran led to a significant reduction in plasma oxalate and pre-dialysis oxalate levels in patients with advanced primary hyperoxaluria type 1 (PH1), according to the 6-month primary analysis of phase III ILLUMINATE-C trial presented at ASN Kidney Week 2021.

Lumasiran reduces plasma oxalate in advanced PH1

25 Nov 2021

Oral daprodustat: A ‘transformative’ care for anaemia in CKD?

24 Nov 2021 by

The oral HIF-PHI* daprodustat was noninferior to standard treatment with erythropoiesis-stimulating agents (ESAs) for increasing haemoglobin levels to within target range, without increasing cardiovascular (CV) risk in patients with anaemia due to chronic kidney disease (CKD), regardless of whether they were dialysis dependent or not, according to the phase III ASCEND-D/-ND trials presented at ASN 2021.

Oral daprodustat: A ‘transformative’ care for anaemia in CKD?

24 Nov 2021

Sotrovimab may reduce COVID-19 disease progression

23 Nov 2021 by

The pan-sarbecovirus monoclonal antibody sotrovimab appears to reduce the risk of COVID-19 disease progression in high-risk patients, according to interim results of the phase III COMET-ICE* trial.

Sotrovimab may reduce COVID-19 disease progression

23 Nov 2021

Dupilumab benefits in EoE sustained through 52 weeks

23 Nov 2021 by

The anti–interleukin (IL)-4/-13 antibody dupilumab led to sustained improvements across symptomatic, histologic, and endoscopic measures of eosinophilic oesophagitis (EoE) out to 52 weeks, according to additional data from the LIBERTY EoE TREET trial presented at ACG 2021.

Dupilumab benefits in EoE sustained through 52 weeks

23 Nov 2021

High-dose corticosteroid good for maintenance treatment in eosinophilic esophagitis

23 Nov 2021 by

Eosinophilic esophagitis patients are likely to experience histological relapse despite ongoing treatment with swallowed topical corticosteroid (STC), but relapse occurs later with high- than with low-dose STC without any increase in side effects, a study has found.

High-dose corticosteroid good for maintenance treatment in eosinophilic esophagitis

23 Nov 2021

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Does COVID-19 vaccine effectiveness wane over time?

Does COVID-19 vaccine effectiveness wane over time?

Community pharmacist intervention helps improve medication adherence

Community pharmacist intervention helps improve medication adherence

Methylprednisolone improves major kidney outcomes in patients with IgAN

Methylprednisolone improves major kidney outcomes in patients with IgAN

6-month single antiplatelet regimen after DAPT post-PCI may reduce GI injury

6-month single antiplatelet regimen after DAPT post-PCI may reduce GI injury

Antihistamine raises appetite in adults

Antihistamine raises appetite in adults

Lumasiran reduces plasma oxalate in advanced PH1

Lumasiran reduces plasma oxalate in advanced PH1

Oral daprodustat: A ‘transformative’ care for anaemia in CKD?

Oral daprodustat: A ‘transformative’ care for anaemia in CKD?

Sotrovimab may reduce COVID-19 disease progression

Sotrovimab may reduce COVID-19 disease progression

Dupilumab benefits in EoE sustained through 52 weeks

Dupilumab benefits in EoE sustained through 52 weeks

High-dose corticosteroid good for maintenance treatment in eosinophilic esophagitis

High-dose corticosteroid good for maintenance treatment in eosinophilic esophagitis