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Corticosteroids up incidence of adverse events, readmissions in severe COPD
A single-institution study does not recommend the prescription of systemic corticosteroids for the treatment of severe acute exacerbation of chronic obstructive pulmonary disease (AECOPD) as this might result in an increased incidence of adverse effects and readmissions.
Niraparib-abiraterone-prednisone combo improves multiple outcomes in HRR+ mCRPC
In patients with metastatic castration-resistant prostate cancer (mCRPC) with homologous recombination repair (HRR) gene alterations*, combining niraparib with abiraterone acetate plus prednisone (AAP) in the first-line setting improved radiographic progression-free survival (rPFS) and other outcomes, results of the phase III MAGNITUDE study showed.
Ustekinumab safe, effective in Asians with severe plaque psoriasis
Ustekinumab, a human monoclonal antibody that binds to the p40 subunit of both interleukin (IL)-12 and IL-23, demonstrates effectiveness and safety in the treatment of multiethnic Asian patients with moderate to severe plaque psoriasis, according to a Singapore study.
Minor changes in glucose levels first week after COVID-19 vaccine
Patients with type 1 diabetes mellitus (T1DM) may experience a temporary change in their blood glucose levels in the first week following COVID-19 vaccination, according to a small English study.