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HCC risk in CHB patients persists 12 years after HBsAg loss
Patients with chronic hepatitis B (CHB) still have a non-negligible risk of hepatocellular carcinoma (HCC) 12 years after achieving hepatitis B surface antigen (HBsAg) seroclearance, especially if cirrhosis is present, a large territory-wide real-world study in Hong Kong has shown.
HCC risk in CHB patients persists 12 years after HBsAg loss
21 Mar 2023
PCSK9 inhibition tied to decreased psoriasis risk
Inhibition of the proprotein convertase subtilisin/kexin type 9 (PCSK9) pathway appears to be causally associated with a lower risk of psoriasis, regardless of the concentration levels of circulating low-density lipoprotein (LDL), according a two-sample Mendelian randomization study.
PCSK9 inhibition tied to decreased psoriasis risk
20 Mar 2023
Telbivudine use during pregnancy safe, effective in HBsAG-positive mothers
Use of telbivudine (LdT) during the second trimester of pregnancy helps prevent mother-to-child transmission of hepatitis B virus, reveals a study. In addition, treatment with LdT during pregnancy is safe in the long term for both mothers and infants.
Telbivudine use during pregnancy safe, effective in HBsAG-positive mothers
20 Mar 2023
Add-on amantadine of no help in hospitalized COVID-19 patients
The addition of amantadine to standard care falls short of improving the likelihood of recovery of patients hospitalized with COVID-19, according to a study.
Add-on amantadine of no help in hospitalized COVID-19 patients
20 Mar 2023
SC trastuzumab cost-saving for HER2-positive breast cancer in Hong Kong
A cost minimization analysis based on a literature review and Hong Kong data suggests that using subcutaneous (CS) instead of intravenous (IV) trastuzumab for HER2-positive breast cancer (BC) patients can offer an annual saving of more than USD 8.3 million to the Hong Kong healthcare system.
SC trastuzumab cost-saving for HER2-positive breast cancer in Hong Kong
20 Mar 2023
Frequent aspirin use protects against ovarian cancer even in women with genetic predisposition
Genetic susceptibility to ovarian cancer does not appear to modify the protective association between frequent aspirin use and the risk of developing the cancer, as shown in a study.