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SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

05 Feb 2025 by

The efficacy of maintenance with a modified biosimilar of infliximab in promoting healing of inflamed mucosa in CD is observed across all SES-CD segments, a post hoc analysis of the LIBERTY-CD trial has shown

SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

05 Feb 2025

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

04 Feb 2025

In patients with colorectal cancer, a history of allergy, previous oxaliplatin exposure, and chemotherapy regimens appear to increase the risk of having oxaliplatin hypersensitivity reactions, results of a recent study have shown.

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

04 Feb 2025

Laparoscopic noninferior to open surgery for low rectal cancer

01 Feb 2025

The disease-free survival outcome in patients with low rectal cancer who receive laparoscopic surgery compares favourably with that in those who receive open surgery, according to a study.

Laparoscopic noninferior to open surgery for low rectal cancer

01 Feb 2025

MAGIC database facilitates understanding of early-life gut microbiome dynamics

28 Jan 2025 by

The Metagenome-Assembled Genome Inventory for Children (MAGIC) database, which contains 20,172 global gut metagenomes from humans aged 0–7 years, characterizes the bacteriome and virome diversity of the global gut microbiome in early life.

MAGIC database facilitates understanding of early-life gut microbiome dynamics

28 Jan 2025

Experimental drug for IBS falls flat in dose-ranging trial

25 Jan 2025

The novel α2δ ligand PD-217,014 does not appear to show any benefit in the treatment of patients with irritable bowel syndrome (IBS) or bowel habit subtypes, irrespective of their pain and anxiety levels, according to a study.

Experimental drug for IBS falls flat in dose-ranging trial

25 Jan 2025

IBD patients prone to develop COPD, asthma

24 Jan 2025 by

Individuals with inflammatory bowel disease (IBD) appear to be at greater risk of developing chronic obstructive pulmonary disease (COPD) and asthma, suggests a study.

IBD patients prone to develop COPD, asthma

24 Jan 2025

One monoclonal antibody outdoes another in real-world ulcerative colitis study

22 Jan 2025 by

The integrin receptor antagonist vedolizumab mostly works as well as the TNF-alpha inhibitor infliximab in biologic-naïve patients with moderate-to-severe ulcerative colitis treated in the real-world setting, although vedolizumab slightly surpasses infliximab in terms of inducing endoscopic response and remission while having a better safety profile, according to a study.

One monoclonal antibody outdoes another in real-world ulcerative colitis study

22 Jan 2025

No increase in CV risk with JAKi vs TNFi for IBD

21 Jan 2025 by

Among patients with inflammatory bowel disease (IBD), treatment with Janus kinase inhibitors (JAKi) does not increase the risk of major adverse cardiovascular events (MACE) compared with tumour necrosis factor inhibitors (TNFi), according to a study presented at AIBD 2024.

No increase in CV risk with JAKi vs TNFi for IBD

21 Jan 2025

Gallstone disease ups IBD risk

20 Jan 2025

People with gallstone disease are at higher risk of inflammatory bowel disease (IBD), regardless of other traditional risk factors, according to a study.

Gallstone disease ups IBD risk

20 Jan 2025

Novel drug for moderate-to-severe UC yields quality-of-life benefits

20 Jan 2025 by

RO7790121, an antibody against tumour necrosis factor-like ligand 1A (Anti-TL1A), helps improve the health-related quality of life (HR-QoL) for patients with moderately to severely active ulcerative colitis (UC), as shown in the phase IIb TUSCANY-2 trial.

Novel drug for moderate-to-severe UC yields quality-of-life benefits

20 Jan 2025

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SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

SC infliximab biosimilar boosts healing along all bowel segments under colonoscopy in CD

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

Allergy history, chemotherapy linked to oxaliplatin hypersensitivity reactions

Laparoscopic noninferior to open surgery for low rectal cancer

Laparoscopic noninferior to open surgery for low rectal cancer

MAGIC database facilitates understanding of early-life gut microbiome dynamics

MAGIC database facilitates understanding of early-life gut microbiome dynamics

Experimental drug for IBS falls flat in dose-ranging trial

Experimental drug for IBS falls flat in dose-ranging trial

IBD patients prone to develop COPD, asthma

IBD patients prone to develop COPD, asthma

One monoclonal antibody outdoes another in real-world ulcerative colitis study

One monoclonal antibody outdoes another in real-world ulcerative colitis study

No increase in CV risk with JAKi vs TNFi for IBD

No increase in CV risk with JAKi vs TNFi for IBD

Gallstone disease ups IBD risk

Gallstone disease ups IBD risk

Novel drug for moderate-to-severe UC yields quality-of-life benefits

Novel drug for moderate-to-severe UC yields quality-of-life benefits