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Motivational interviewing plus CBT eases negative symptoms in schizophrenia
Motivational interviewing (MI) in combination with cognitive behavioural therapy (CBT) improves negative symptoms in patients with schizophrenia, reports a study. These symptoms are initially thought of as resistant to any intervention.
Donanemab BLAZEs through Alzheimer’s treatment TRAIL in first active comparator trial
The first study to directly compare two disease-modifying agents for Alzheimer’s disease (AD), the phase III TRAILBLAZER-ALZ 4 study shows promising efficacy and safety data on donanemab vs aducanumab for the treatment of early symptomatic AD.
Gut dysbiosis evident in patients with prodromal PD and their first-degree relatives
A cross-sectional study from the Chinese University of Hong Kong suggests that Parkinson’s disease (PD)–like gut dysbiosis occurs at preclinical prodromal stages of PD, in patients with video-polysomnography (v-PSG)–confirmed REM sleep behavior disorder (RBD) and even in their younger first-degree relatives (RBD-FDR).
Cash transfers ease functional impairment in elderly
A study in India has shown the effectiveness of a small cash transfer in alleviating short-term functional impairment among older people who are living alone. However, cash transfers do not produce a clinically or statistically significant decrease in depression and show no impact on food security.
