News & Updates

Use of foetal echocardiograms results in an accurate diagnosis of congenital heart diseases (CHDs), with good concordance between pre- and postnatal diagnoses, according to a Singapore study.

A recent study recommends having a high index of suspicion for Pott’s puffy tumour (PPT), a rare complication of frontal sinusitis, among adolescents who present with prolonged headache or frontal swelling.

New drug applications approved by US FDA as of 15-30 September 2023 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

A common incidental discovery during upper endoscopy for the diagnosis of common paediatric gastrointestinal (GI) diseases is Helicobacter pylori (H pylori) gastritis, a recent study has revealed. However, indications for treatment are not clear and warrant further research.

A 20-year retrospective study in Hong Kong has shown that renal relapse generally occurs within the first 5 years after diagnosis of childhood-onset lupus nephritis (cLN) in Chinese patients. The risk of renal relapse is higher in those diagnosed at young age, those failing to achieve complete remission (CR) 12 months after induction therapy, and those receiving maintenance therapy other than mycophenolate mofetil (MMF).

Exposure to acid-suppressive therapy during the first year of life appear to come with a small but significant increase in the risk of fractures, according to a study.

Multistrain probiotics confer significant mortality-reduction benefit in preterm infants, according to the results of a network meta-analysis.

In a prospective study by the University of Hong Kong, long-term prophylaxis (LTP) with garadacimab or lanadelumab reduces attacks and improves quality of life (QoL) in Chinese patients with hereditary angioedema (HAE) who experienced frequent attacks. No adverse events (AEs) were reported.

First-line treatment with dabrafenib plus trametinib significantly increased overall response rate (ORR) in paediatric patients with low-grade glioma harbouring BRAF V600 mutations compared with standard chemotherapy, according to a recent study.