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Transmembrane modulators of CFTR gene leads to improvements in kids with cystic fibrosis

07 Jul 2022 by

Using small molecule drugs to modulate the cystic fibrosis transmembrane conductance regulator (CFTR) protein improves multiple aspects of cystic fibrosis in paediatric patients, including lung function, CFTR protein function, and nutritional status, according to a recent meta-analysis.

Transmembrane modulators of CFTR gene leads to improvements in kids with cystic fibrosis

07 Jul 2022

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

06 Jul 2022

Children with ulcerative colitis seem to respond well to vedolizumab in the first-line setting, inducing remission without increasing the risk of adverse events, according to a small study.

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

06 Jul 2022

High-dose zinc intake tied to less feeding intolerance in VLBW infants

06 Jul 2022 by

High-dose zinc supplementation was significantly associated with decreased feeding intolerance in very low birth weight (VLBW) preterm infants, according to a study presented at ESPGHAN 2022.

High-dose zinc intake tied to less feeding intolerance in VLBW infants

06 Jul 2022

$Inotuzumab ozogamicin safe, effective in relapsed, refractory paediatric ALL$

Inotuzumab ozogamicin safe, effective in relapsed, refractory paediatric ALL

05 Jul 2022

Inotuzumab ozogamicin is well tolerated and demonstrates clinical activity in children with relapsed or refractory acute lymphoblastic leukaemia (ALL), according to the results of a phase II trial.

Inotuzumab ozogamicin safe, effective in relapsed, refractory paediatric ALL

05 Jul 2022

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

05 Jul 2022 by

The combination of two targeted therapies, dabrafenib and trametinib, significantly improves the overall response rate (ORR) in paediatric patients with low-grade glioma (LGG) with BRAF V600 mutations compared with the combination of standard chemotherapy drugs, according to a study presented at ASCO 2022.

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

05 Jul 2022

Portable bladder ultrasound device provides accurate measurements in toddlers

04 Jul 2022 by

The children’s module of the Bladder Scanner (BS), a portable ultrasound device used to measure bladder volume, shows acceptable accuracy in children 4 years of age and above, according to a recent study. However, device performance appears unreliable in younger children.

Portable bladder ultrasound device provides accurate measurements in toddlers

04 Jul 2022

$BTX-A safe, effective for kids with refractory OAB$

BTX-A safe, effective for kids with refractory OAB

03 Jul 2022

Children with refractory overactive bladder (OAB) benefit from botulinum toxin-A (BTX-A) injections, which can safely enlarge bladder and suppress OAB symptoms, a recent study has found.

BTX-A safe, effective for kids with refractory OAB

03 Jul 2022

Nitric oxide during heart surgery of no benefit in young kids

02 Jul 2022

The delivery of nitric oxide into the cardiopulmonary bypass in young children undergoing surgery for congenital heart disease does not significantly reduce the number of ventilator-free days, as shown in a study.

Nitric oxide during heart surgery of no benefit in young kids

02 Jul 2022

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

02 Jul 2022

The routine implementation of cerebral magnetic resonance imaging (cMRI) commonly detects low-grade abnormalities in extremely premature infants, such as low-grade intraventricular haemorrhage (IVH), white matter disease (WMD), and cerebellar injury (CBI), a new study has found.

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

02 Jul 2022

COVID-19 shots for tots OK’d

01 Jul 2022 by

The 2-year wait is over.

COVID-19 shots for tots OK’d

01 Jul 2022

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Transmembrane modulators of CFTR gene leads to improvements in kids with cystic fibrosis

Transmembrane modulators of CFTR gene leads to improvements in kids with cystic fibrosis

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

High-dose zinc intake tied to less feeding intolerance in VLBW infants

High-dose zinc intake tied to less feeding intolerance in VLBW infants

Inotuzumab ozogamicin safe, effective in relapsed, refractory paediatric ALL

Inotuzumab ozogamicin safe, effective in relapsed, refractory paediatric ALL

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

Novel targeted therapy shows better response than chemo in BRAF V600-mutant paediatric LGG

Portable bladder ultrasound device provides accurate measurements in toddlers

Portable bladder ultrasound device provides accurate measurements in toddlers

BTX-A safe, effective for kids with refractory OAB

BTX-A safe, effective for kids with refractory OAB

Nitric oxide during heart surgery of no benefit in young kids

Nitric oxide during heart surgery of no benefit in young kids

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

Routine cerebral magnetic resonance imaging catches low-grade pathologies in preemies

COVID-19 shots for tots OK’d

COVID-19 shots for tots OK’d