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Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

15 May 2022

Urgency, or the immediate need to defecate, in patients with ulcerative colitis (UC) is an independent predictor of compromised quality of life (QoL) and future risk of hospitalizations, corticosteroid use, and colectomy, suggests a study.

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

15 May 2022

Long-term aspirin use lowers HCC risk in chronic HBV patients

14 May 2022

Use of aspirin in the long term appears to markedly reduce the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV), a study has shown.

Long-term aspirin use lowers HCC risk in chronic HBV patients

14 May 2022

Radiologic features predict more necrosectomies in walled-off necrosis

11 May 2022

Several features of computed tomography (CT) imaging are significantly predictive of undergoing at least two necrosectomy sessions for patients with walled-off pancreatic necrosis (WON), suggest the results of a recent study.

Radiologic features predict more necrosectomies in walled-off necrosis

11 May 2022

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

10 May 2022

A short intervention that addresses the nocebo (negative placebo) effect appears to improve tolerance of tricyclic antidepressants (TCAs), which are commonly used to treat disorders of gut-brain interaction (DGBI), a study has shown.

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

10 May 2022

Norfloxacin prevents bacterial infections in patients with liver failure

10 May 2022 by

Primary norfloxacin prophylaxis is both safe and effective in preventing bacterial infections in patients with acute-on-chronic liver failure (ACLF), a study has shown.

Norfloxacin prevents bacterial infections in patients with liver failure

10 May 2022

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

10 May 2022

Outlet dysfunction is associated with suboptimal bowel preparation and decreased cecal intubation, among others, in patients with chronic constipation undergoing colonoscopy, reveals a study.

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

10 May 2022

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

06 May 2022 by

Adding adebrelimab to chemotherapy improves survival outcomes over chemotherapy alone in patients with extensive-stage small cell lung cancer (SCLC) in the phase III CAPSTONE-1 study presented at AACR 2022. This brings hope to SCLC patients with limited treatment options and poor prognoses.

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

06 May 2022

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

05 May 2022

The stools of asymptomatic patients carry the most common viruses that cause gastroenteritis in children and serve as a potential reservoir for acute gastroenteritis (AGE), a study has shown.

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

05 May 2022

Original New Drug Application Approvals by US FDA (16 - 30 April 2022)

05 May 2022

New drug applications approved by US FDA as of 16-30 April 2022 which includes New Molecular Entities (NMEs) and new biologics. It does not include Tentative Approvals. Supplemental approvals may have occurred since the original approval date.

Original New Drug Application Approvals by US FDA (16 - 30 April 2022)

05 May 2022

Guselkumab promising for Crohn’s disease

28 Apr 2022

In Crohn’s disease patients with inadequate response or intolerance to conventional or biologic therapy, guselkumab, a selective p19 interleukin (IL)-23 antagonist, appears effective by yielding better clinical and endoscopic improvements than placebo, a recent study has found.

Guselkumab promising for Crohn’s disease

28 Apr 2022

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Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

Urgency tied to poorer quality of life, ups hospitalization risk in UC patients

Long-term aspirin use lowers HCC risk in chronic HBV patients

Long-term aspirin use lowers HCC risk in chronic HBV patients

Radiologic features predict more necrosectomies in walled-off necrosis

Radiologic features predict more necrosectomies in walled-off necrosis

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

Educating about nocebo effects helps improve tolerance to tricyclic antidepressants

Norfloxacin prevents bacterial infections in patients with liver failure

Norfloxacin prevents bacterial infections in patients with liver failure

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

Rectal evacuation disorders tied to poor bowel preparation in chronic constipation patients

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

Adebrelimab plus chemo almost doubles OS, triples PFS in extensive-stage SCLC

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

Viruses causing gastroenteritis in children thrive in stools of asymptomatic carriers

Original New Drug Application Approvals by US FDA (16 - 30 April 2022)

Original New Drug Application Approvals by US FDA (16 - 30 April 2022)

Guselkumab promising for Crohn’s disease

Guselkumab promising for Crohn’s disease