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SARS-CoV-2 antigen tests exhibit moderate-to-high sensitivity vs RT-PCR, cultures
Home antigen tests for SARS-CoV-2 infection were moderately sensitive compared with RT-PCR* test but highly sensitive compared with viral culture in adults and children with RT-PCR-confirmed infection, a prospective study suggests.

Long COVID: What factors contribute to the risk?
Only a minority of patients are considered fully recovered 1 year after being discharged from hospital due to COVID-19, with women and obese individuals at increased risk of long COVID, according to results of the prospective PHOSP-COVID* study presented at ECCMID 2022 and published in The Lancet.

Fewer hospitalizations with omicron vs delta suggest reduced severity of omicron variant
Infection with the omicron variant of SARS-CoV-2 was less likely to result in hospitalization than infection with the delta variant, according to an observational study from Denmark presented at ECCMID 2022 and published in The Lancet.

COVID-19 vaccine booster efficacy: What do new HK data show?
A booster dose of the mRNA-based BNT162b2 vaccine provides more robust antibody responses to SARS-CoV-2, including the Omicron BA.1 and BA.2 variants, than the inactivated CZ02 vaccine, but three doses of either vaccine are equally effective in reducing the risk of severe or fatal COVID-19, according to new local data presented at the 26th Hong Kong Medical Forum (HKMF).

Male sex, obesity among risk factors for severe COVID-19 in children
A large study by the US National COVID Cohort Collaborative (N3C) has identified factors associated with the risk of severe disease among children with SARS-CoV-2 infection as well as factors tied to an increased risk of multisystem inflammatory syndrome in children (MIS-C) as compared to acute COVID-19.



