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Trastuzumab deruxtecan shows promise in metastatic breast cancer
Treatment with trastuzumab deruxtecan (T-DXd) provides sustained antitumour activity and shows a consistent safety profile in patients with human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (mBC) previously treated with trastuzumab emtansine (T-DM1), as shown by the updated survival results from the phase II DESTINY-Breast01 trial.
Trastuzumab deruxtecan shows promise in metastatic breast cancer
03 Mar 2024Is MFS a valid surrogate for OS in prostate cancer?
Metastasis-free survival (MFS) is still a good proxy for overall survival (OS) as endpoint in the current era, wherein patients have more access to docetaxel and other treatments for metastatic castrate-resistant prostate cancer (mCRPC), according to a study.
Is MFS a valid surrogate for OS in prostate cancer?
02 Mar 2024Which factors predict mortality in advanced HCC?
A study has found the high bilirubin, pretreatment hypoalbuminemia, and biochemical tests indicative of hepatic or renal dysfunctions are independently associated with short-term mortality in patients with advanced hepatocellular cancer (HCC) receiving atezolizumab and bevacizumab (Atezo/Bev).
Which factors predict mortality in advanced HCC?
01 Mar 2024Nivolumab plus ipilimumab superior to sunitinib in advanced RCC
First-line treatment with nivolumab plus ipilimumab (NIVO+IPI) results in better survival and response benefits in patients with advanced renal cell carcinoma (aRCC) when compared with sunitinib (SUN), as shown by long-term follow-up data from the CheckMate 214 trial.
Nivolumab plus ipilimumab superior to sunitinib in advanced RCC
01 Mar 2024Interactive multistage robotic positioner developed for intraoperative MRI-guided stereotactic neurosurgery
A joint multidisciplinary team of researchers from the Chinese University of Hong Kong (CUHK), the University of Hong Kong (HKU), University College London, and Johns Hopkins University has developed an interactive, multistage robotic positioner for intraoperative MRI-guided stereotactic neurosurgery aimed at treating patients with neurological diseases, such as brain tumours and Parkinson’s disease.