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Certain ART combinations carry some risk of depression among women with HIV
Women with HIV who use antiretroviral therapy (ART) combinations such as tenofovir alafenamide (TAF) with a cobicistat-boosted integrase inhibitor (INSTI) or protease inhibitor (PI) appear to frequently show somatic depressive symptoms, according to data from the Women’s Interagency HIV Study (WIHS) presented at CROI 2023.
Certain ART combinations carry some risk of depression among women with HIV
31 Mar 2023Oral HBV cccDNA inhibitor a promising cure against chronic HBV infection
A recent study has found a small-molecule covalently closed circular DNA (cccDNA) inhibitor that reduces levels of hepatitis B virus (HBV) cccDNA. This discovery offers a new way to cure patients with chronic HBV infection.
Oral HBV cccDNA inhibitor a promising cure against chronic HBV infection
31 Mar 2023Ceftolozane/tazobactam safe, effective in complicated UTI
Combination therapy with ceftolozane and tazobactam demonstrates a favourable safety profile in children with complicated urinary tract infection (cUTI) similar to that of meropenem and to the previously reported safety profile in adults with cUTI, a study has shown.
Ceftolozane/tazobactam safe, effective in complicated UTI
30 Mar 2023Remdesivir cuts mortality in COVID-19 patients requiring no or low-flow oxygen
In a systematic review and individual patient data meta-analysis, the broad-spectrum antiviral agent remdesivir reduced mortality in adult patients hospitalized for COVID-19 who did not require oxygen support or only required low-flow supplementation when the need for oxygen arose.
Remdesivir cuts mortality in COVID-19 patients requiring no or low-flow oxygen
30 Mar 2023How does gel stent perform vs trabeculectomy in open-angle glaucoma?
In the treatment of patients with open-angle glaucoma (OAG), gel stent is noninferior to trabeculectomy in terms of reducing intraocular pressure (IOP) by at least 20 percent, according to a study. Trabeculectomy helps reduce IOP to a greater extent, whereas gel stent leads to fewer adverse events (AEs).