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Add-on mRNA cancer vaccine delivers promise for melanoma
Adding mRNA-4157, an investigational personalized neoantigen cancer vaccine, to the immune checkpoint inhibitor (ICI) pembrolizumab significantly improved recurrence-free survival (RFS) in individuals with resected high-risk melanoma, findings from the phase IIb KEYNOTE 942 study suggest.
Add-on mRNA cancer vaccine delivers promise for melanoma
20 Jun 2023Atopic dermatitis poses heightened risk of venous thromboembolism
Adults with atopic dermatitis appear to have an increased risk of venous thromboembolism (VTE), although the risk difference relative to adults without AD is quite small, as reported in a study.
Atopic dermatitis poses heightened risk of venous thromboembolism
03 Jun 2023Cytokine profile tied to treatment response in eczematous dermatitis
The baseline skin cytokine profile of patients with eczematous dermatitis, as determined by RNA in situ hybridization, can help predict response to dupilumab therapy, results of a study have shown.
Cytokine profile tied to treatment response in eczematous dermatitis
31 May 2023Functional surgery delivers amputation-free benefit in nail unit melanoma
Patients who have nail unit melanoma (NUM) with a Breslow thickness (BT) of <0.8 mm may benefit from functional surgery, which offers an amputation-sparing advantage, suggests a recent study.
Functional surgery delivers amputation-free benefit in nail unit melanoma
29 May 2023HCT treatment tied to lower cancer risk, except skin cancer
Treatment with hydrochlorothiazide (HCT) contributes to a lower all-cancer risk and a slightly higher skin cancer risk compared with alternative diuretics, reports a study involving a German population.
HCT treatment tied to lower cancer risk, except skin cancer
26 May 2023Vitamin D supplementation exerts no effect on psoriasis severity in vitamin D-deficient individuals
Supplementation with vitamin D falls short of reducing psoriasis severity for individuals with 25-hydroxyvitamin D (25[OH]D) levels of <24 ng/mL, as reported in a study.