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Asian-derived polygenic risk scores boost risk stratification for breast cancer
Drawing from the largest available studies of Asian breast cancer patients, a recent Singapore study has developed polygenic risk scores (PRS) that can help improve the risk stratification of women of Asian ancestry.
Asian-derived polygenic risk scores boost risk stratification for breast cancer
27 Dec 2021
Sintilimab-IBI305-chemo improves PFS in EGFRm non-squamous NSCLC
The combination of the anti-PD-1 monoclonal antibody sintilimab with the bevacizumab biosimilar IBI305 and pemetrexed and cisplatin chemotherapy improved progression-free survival (PFS) in patients with EGFR*-mutated (EGFRm) non-squamous non-small-cell lung cancer (NSCLC), according to interim analysis results of the phase III ORIENT-31 trial from China.
Sintilimab-IBI305-chemo improves PFS in EGFRm non-squamous NSCLC
24 Dec 2021
Repeat surgery plus chemo may improve survival in recurrent ovarian cancer
The DESKTOP* III trial has shown that patients whose ovarian cancer recurs have better overall survival (OS) following secondary cytoreductive surgery plus platinum-based chemotherapy compared with a platinum-based chemotherapy regimen alone.
Repeat surgery plus chemo may improve survival in recurrent ovarian cancer
23 Dec 2021
Aumolertinib a win in EGFR T790M-positive advanced NSCLC
The novel third-generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) aumolertinib appears to be effective in the treatment of patients with EGFR T790M-positive advanced nonsmall cell lung carcinoma (NSCLC) following progression on first- and second-generation EGFR TKI therapy, according to data from the phase II APOLLO Registrational Trial.
Aumolertinib a win in EGFR T790M-positive advanced NSCLC
23 Dec 2021
New algorithm predicts HCC risk in compensated advanced chronic liver disease
A novel algorithm using post-treatment age, albumin, and liver stiffness measurement (LSM), among other parameters, can accurately stratify patients with compensated advanced chronic liver disease (cACLD) according to their de novo hepatocellular carcinoma (HCC) risk, a new study shows.
New algorithm predicts HCC risk in compensated advanced chronic liver disease
19 Dec 2021
Remote management during chemotherapy fails to reduce ED visits, hospitalization
A remote, proactive, and telephone-based management of toxicities in outpatients during adjuvant or neoadjuvant chemotherapy for early-stage breast cancer does not lead to fewer visits to the emergency department (ED) or hospital admissions, a study has shown.