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B/F/TAF safe, effective in adults with high HIV-1 RNA, low CD4 count
Adults with a high baseline HIV-1 RNA or low CD4 count may benefit from initial treatment with bictegravir/emtricitabine/tenofovir alafenamide (B/F/TAF), which has been shown to be safe and efficacious over 5 years of follow-up in a study presented at the ID Week 2022 Virtual Conference.
B/F/TAF safe, effective in adults with high HIV-1 RNA, low CD4 count
27 Oct 2022Ridinilazole triggers clinical response in CDI, inhibits recurrence
In patients with Clostridioides difficile infections (CDI), treatment with ridinilazole (RDZ) leads to high and sustained rates of clinical response, according to a study presented at the recently concluded Virtual ID Week 2022. Compared with vancomycin (VAN), RDZ also more strongly prevents recurrent CDI (rCDI).
Ridinilazole triggers clinical response in CDI, inhibits recurrence
27 Oct 2022Vitamin D, aspirin, exercise reduce pregnancy-related hypertension
There appears to be several ways to reduce the risk of pre-eclampsia and pregnancy-induced hypertension. These include low molecular weight heparin (LMWH), vitamin D supplementation, calcium supplementation, aspirin, and exercise, according to a meta-analysis.
Vitamin D, aspirin, exercise reduce pregnancy-related hypertension
27 Oct 2022Statins show therapeutic potential in COVID-19-related acute kidney injury
COVID-19 patients with chronic statin exposure appear to be at lower risk of developing acute kidney injury (AKI) during hospitalization in addition to having reduced levels of inflammation, as reported in a study.
Statins show therapeutic potential in COVID-19-related acute kidney injury
26 Oct 2022Tenofovir alafenamide reduces liver stiffness in CHB patients
Treatment with the nucleos(t)ide analogue (NUC) tenofovir alafenamide (TAF) for 2 years leads to improvements in liver stiffness among patients with chronic hepatitis B (CHB), including those with advanced liver fibrosis, according to a study presented at the IDWeek 2022 in Washington, DC, US.
Tenofovir alafenamide reduces liver stiffness in CHB patients
26 Oct 2022Cefepime-taniborbactam trumps meropenem for complicated UTI
Cefepime-taniborbactam (FTB) is significantly better than meropenem for the treatment of complicated urinary tract infections (cUTI) and acute pyelonephritis (AP), according to results of the Cefepime Rescue with Taniborbactam in cUTI (CERTAIN-1) study presented at the recent ID Week 2022.