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Is there a need to re-evaluate HbA1c cutoff in premenopausal women?
In an analysis of over a million individuals in England, women aged <50 years had a markedly lower HbA1c distribution than men, suggesting that the application of the current HbA1c reference range may lead to underdiagnosis of type 2 diabetes (T2D) in premenopausal women.
Is there a need to re-evaluate HbA1c cutoff in premenopausal women?
18 Oct 2023Dapagliflozin cuts HbA1c in paediatric T2D
Dapagliflozin reduced HbA1c by 1.03 percentage points more than placebo in children and adolescents with type 2 diabetes (T2D), while saxagliptin showed no significant reduction vs placebo in the phase III T2NOW trial presented at EASD 2023.
Dapagliflozin cuts HbA1c in paediatric T2D
17 Oct 2023Finerenone confers cardiorenal benefits in Chinese CKD, T2D patients
In the subgroup analysis of the phase III FIGARO-DKD trial, the selective nonsteroidal mineralocorticoid receptor antagonist finerenone conferred cardiorenal benefits in Chinese patients with chronic kidney disease (CKD) and type 2 diabetes (T2D). The findings were consistent with that observed in the overall cohort.
Finerenone confers cardiorenal benefits in Chinese CKD, T2D patients
16 Oct 2023Shorter height, smaller hips linked to higher T2D risk
Most adiposity markers are positively associated with incident type 2 diabetes (T2D), but waist to height ratio (WHtR) shows the most robust association and is a better predictor of T2D risk.
Shorter height, smaller hips linked to higher T2D risk
15 Oct 2023Physical activity in the morning more effective in preventing obesity than at night
Moderate-to-vigorous physical activity (MVPA) in the morning appears to be more protective against obesity, particularly for individuals who are sedentary for most of the day, a study has found.
Physical activity in the morning more effective in preventing obesity than at night
14 Oct 2023Understanding the effects of LDL-C lowering on several diseases
Genetic evidence confirms both the positive and negative associations of low-density lipoprotein cholesterol (LDL-C) reduction with certain metabolic and cardiovascular diseases (CVDs), according to the results of a Mendelian randomization (MR) study in the UK Biobank.
Understanding the effects of LDL-C lowering on several diseases
13 Oct 2023Resistance exercise prevents ADT-induced muscle loss in patients with prostate cancer
Resistance exercise training counters the negative effects of androgen deprivation therapy (ADT) and improves muscle fibre size, as well as capillarization, in patients with prostate cancer, reports a study.
Resistance exercise prevents ADT-induced muscle loss in patients with prostate cancer
09 Oct 2023Liraglutide vs semaglutide: Which is a better GLP-1 RA for diabetic veterans?
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) liraglutide and semaglutide are both effective at lowering haemoglobin A1c (A1c) among veterans with type 2 diabetes mellitus (T2DM), reports a recent study, which provides insights into key considerations for this population.