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Apremilast more efficacious in PsA patients with moderate vs high disease activity
Psoriatic arthritis (PsA) patients with moderate disease activity (MDA) at baseline who are treated with apremilast are more likely to achieve treatment targets than those with high disease activity (HDA), a recent study has shown.
Apremilast more efficacious in PsA patients with moderate vs high disease activity
22 Jul 20226-month secukinumab use improves outcomes in psoriatic arthritis
Real-world patients with psoriatic arthritis (PsA) who received and remained on secukinumab treatment for 6 months has attained minimal disease activity (MDA) and shown improvements in clinical manifestations, patient-reported outcomes, and work productivity at follow-up, reveals a study. The results are consistent with findings from clinical trials.
6-month secukinumab use improves outcomes in psoriatic arthritis
21 Jul 2022Which factors predict hospitalization for acute gout?
Several factors, including older age, overnight emergency department (ED) arrival time, higher serum urate (SU), higher C-reactive protein (CRP), and higher total white cell count at presentation, predict hospitalization for acute gout, according to a study.
Which factors predict hospitalization for acute gout?
21 Jul 2022Smoking, comorbidities, EAMs up death risk in hospitalized ankylosing spondylitis patients
Smoking, extra-articular manifestations (EAMs), and comorbidities are all associated with a higher risk of all-cause mortality in hospitalized patients with ankylosing spondylitis (AS) than those in the comparison cohort, reports a study.
Smoking, comorbidities, EAMs up death risk in hospitalized ankylosing spondylitis patients
20 Jul 2022Older age, lower BMI, seropositivity tied to RA-related bronchiectasis
Isolated bronchiectasis (BR) in rheumatoid arthritis (RA) that is not caused by interstitial lung disease (ILD) is associated with seropositivity, older age at RA diagnosis, and lower body mass index (BMI) at RA onset, a recent study has found.
Older age, lower BMI, seropositivity tied to RA-related bronchiectasis
20 Jul 2022Upadacitinib works in select ankylosing spondylitis patients
The Janus kinase inhibitor upadacitinib induces significantly higher response than placebo in ankylosing spondylitis patients with inadequate response to biological disease-modifying antirheumatic drugs, without introducing new safety signals, according to data from a phase III trial.
Upadacitinib works in select ankylosing spondylitis patients
14 Jul 2022Ozoralizumab shows therapeutic potential in rheumatoid arthritis
Treatment with the next-generation anti-TNFα antibody yields marked improvements in the signs and symptoms of rheumatoid arthritis in patients with inadequate response to methotrexate (MTX), while having an acceptable safety profile, as shown in the phase II/III OHZORA trial.
Ozoralizumab shows therapeutic potential in rheumatoid arthritis
13 Jul 2022RA patient’s perspective must be respected in treatment decisions, says study
Physician-reported measures on responses to tofacitinib and adalimumab treatments are higher than those reported by patients with rheumatoid arthritis (RA), according to a post hoc analysis of data from phase III and phase IIIb/IV trials.
RA patient’s perspective must be respected in treatment decisions, says study
07 Jul 2022Distinct plasma vs gut microbiome seen in SLE patients, healthy individuals
A distinct community and greater heterogeneity have been observed in the plasma microbiome compared to the gut in both patients with systemic lupus erythematosus (SLE) and healthy individuals, reports a recent study. This suggests that the predominant circulating microbiome may originate from sites other than the gastrointestinal tract.