News & Updates

TTFields use in special GBM populations and potential combination with immunotherapy

14 Feb 2023 by

Glioblastoma multiforme (GBM) is the most common and aggressive brain tumour with a very poor prognosis. Tumour-treating fields (TTFields) are a relatively new, noninvasive treatment for GBM, which delivers low-intensity alternating electric fields that disrupt cancer cell division. At a recent scientific meeting organized by the Hong Kong Neurosurgical Society, Dr Alexander Grote of the Department of Neurosurgery, University Hospital of Marburg, Germany, and Professor Michael Lim of the Department of Neurosurgery, Stanford University, US, discussed the evolving role of TTFields in managing patients with GBM.

TTFields use in special GBM populations and potential combination with immunotherapy

14 Feb 2023

First-line NALIRIFOX regimen ups survival in metastatic pancreatic cancer

14 Feb 2023 by

The use of liposomal irinotecan in combination with 5-fluorouracil, leucovorin, and oxaliplatin (NALIRIFOX regimen) significantly improved overall survival (OS) and progression-free survival (PFS) in patients with metastatic pancreatic ductal adenocarcinoma (mPDAC) compared with gemcitabine plus nab-paclitaxel (Gem+NabP) in the first-line setting, according to the NAPOLI-3* trial presented at the ASCO GI 2023.

First-line NALIRIFOX regimen ups survival in metastatic pancreatic cancer

14 Feb 2023

$Hyaluronic acid rectal spacer improves safety outcomes of hypofractionated RT for prostate cancer$

Hyaluronic acid rectal spacer improves safety outcomes of hypofractionated RT for prostate cancer

13 Feb 2023

Rectal spacing with hyaluronic acid helps lessen rectal dosimetry and mitigate the gastrointestinal (GI) toxicity associated with hypofractionated radiation therapy (RT) for prostate cancer, according to a study.

Hyaluronic acid rectal spacer improves safety outcomes of hypofractionated RT for prostate cancer

13 Feb 2023

1 in 4 cardiologists struggle with mental health conditions, says study

13 Feb 2023

Mental health conditions (MHCs) befall many cardiologists globally, which may lead to substantial adverse effects on their professional life, reveals a study.

1 in 4 cardiologists struggle with mental health conditions, says study

13 Feb 2023

Early antibiotics does not prevent infection in hospitalized cirrhosis patients

13 Feb 2023 by

Antibiotics are usually prescribed by physicians to patients hospitalized with decompensated cirrhosis even without an infection diagnosis, according to a UK study. However, this practice has neither reduced the overall risk of hospital-acquired infections (HAI) nor improved survival.

Early antibiotics does not prevent infection in hospitalized cirrhosis patients

13 Feb 2023

Nitrofurantoin use tied to liver injury, may lead to cirrhosis, death

13 Feb 2023

Long-term exposure to nitrofurantoin (NTF) can result in drug-induced liver injury (DILI), which then increases the risk of parenchymal necrosis, bridging fibrosis, cirrhosis, and death or liver transplantation, reveals a study. In addition, NTF-DILI is associated with HLA-DRB1∗11:04, a risk factor for liver injury.

Nitrofurantoin use tied to liver injury, may lead to cirrhosis, death

13 Feb 2023

Shorter treatment regimen feasible for rifampin-resistant TB?

13 Feb 2023 by

Individuals with rifampin-resistant tuberculosis (RR-TB) may have the option to undergo shorter treatment periods, as findings from the phase II/III TB-PRACTECAL* trial show the noninferiority and superiority of a 24-week, all-oral regimen to standard of care (SoC). It also had a better safety profile than SoC.

Shorter treatment regimen feasible for rifampin-resistant TB?

13 Feb 2023

IV iron for chemo-induced anaemia: Ready for primetime?

13 Feb 2023 by

Intravenous (IV) iron reduces the need for red blood cell (RBC) transfusions in patients with chemotherapy-induced anaemia (CIA), without any difference in adverse events (AEs), compared with oral iron or placebo in a new study.

IV iron for chemo-induced anaemia: Ready for primetime?

13 Feb 2023

Weight loss surgery may raise life expectancy

13 Feb 2023 by

For individuals with obesity, weight loss surgery may prevent premature death and improve chances of having a longer life.

Weight loss surgery may raise life expectancy

13 Feb 2023

Low-carb diet ups testosterone levels, erectile function in hypogonadal men

13 Feb 2023

Following a low-carbohydrate diet helps in male hypogonadism by increasing serum levels of testosterone and improving erectile function for hypogonadal men with metabolic syndrome, as shown in a study.

Low-carb diet ups testosterone levels, erectile function in hypogonadal men

13 Feb 2023

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TTFields use in special GBM populations and potential combination with immunotherapy

TTFields use in special GBM populations and potential combination with immunotherapy

First-line NALIRIFOX regimen ups survival in metastatic pancreatic cancer

First-line NALIRIFOX regimen ups survival in metastatic pancreatic cancer

Hyaluronic acid rectal spacer improves safety outcomes of hypofractionated RT for prostate cancer

Hyaluronic acid rectal spacer improves safety outcomes of hypofractionated RT for prostate cancer

1 in 4 cardiologists struggle with mental health conditions, says study

1 in 4 cardiologists struggle with mental health conditions, says study

Early antibiotics does not prevent infection in hospitalized cirrhosis patients

Early antibiotics does not prevent infection in hospitalized cirrhosis patients

Nitrofurantoin use tied to liver injury, may lead to cirrhosis, death

Nitrofurantoin use tied to liver injury, may lead to cirrhosis, death

Shorter treatment regimen feasible for rifampin-resistant TB?

Shorter treatment regimen feasible for rifampin-resistant TB?

IV iron for chemo-induced anaemia: Ready for primetime?

IV iron for chemo-induced anaemia: Ready for primetime?

Weight loss surgery may raise life expectancy

Weight loss surgery may raise life expectancy

Low-carb diet ups testosterone levels, erectile function in hypogonadal men

Low-carb diet ups testosterone levels, erectile function in hypogonadal men