News & Updates

T-cell exhaustion tied to post-BCG recurrence in bladder cancer
T-cell exhaustion tied to post-BCG recurrence in bladder cancer
07 Nov 2022 byTristan Manalac

In patients with non-muscle-invasive bladder cancer (NMIBC), high-grade (HG) recurrence after bacillus Calmette-Guérin (BCG) treatment is associated with T-cell exhaustion, according to a study.

T-cell exhaustion tied to post-BCG recurrence in bladder cancer
07 Nov 2022
Alcohol-related liver disease poses increased risk of cardiovascular disease
Alcohol-related liver disease poses increased risk of cardiovascular disease
07 Nov 2022

Patients with biopsy-proven alcohol-related liver disease (ALD) appear to have a higher frequency of cardiovascular disease (CVD) than their counterparts without ALD, according to a study. The increased rates are especially pronounced just after ALD diagnosis.

Alcohol-related liver disease poses increased risk of cardiovascular disease
07 Nov 2022
Varenicline nasal spray improves bilateral tear production in dry eye disease
Varenicline nasal spray improves bilateral tear production in dry eye disease
07 Nov 2022

Treatment with OC-01 (varenicline solution) nasal spray in patients with dry eye results in a substantial increase in tear production in the study eyes as well as in milder presenting nonstudy fellow eyes, according to data from the ONSET-1* and ONSET-2 trials.

Varenicline nasal spray improves bilateral tear production in dry eye disease
07 Nov 2022
Donor hypertension worsens graft survival, function in kidney recipients
Donor hypertension worsens graft survival, function in kidney recipients
06 Nov 2022

Kidney transplant recipients from living donors with hypertension are at significantly increased risk of renal allograft loss compared to those from normotensive living donors, reveals a study. Moreover, outcomes are similar to recipients of normotensive deceased donors.

Donor hypertension worsens graft survival, function in kidney recipients
06 Nov 2022
Statin use linked to reduced risk of severe COVID-19 outcomes
Statin use linked to reduced risk of severe COVID-19 outcomes
06 Nov 2022 byRoshini Claire Anthony

Patients who are on long-term statin therapy may have a reduced risk of severe COVID-19–related outcomes including mortality, intensive care unit (ICU) admission, and requirement for mechanical ventilation, according to a study presented at Anesthesiology 2022.

Statin use linked to reduced risk of severe COVID-19 outcomes
06 Nov 2022
Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
06 Nov 2022

A third-dose administration of a COVID-19 mRNA vaccine results in a more substantial decrease in COVID-19 in patients with cirrhosis compared with the general population, according to a study. This suggests that the third dose can overcome vaccine hyporesponsiveness in this population.

Third-dose vaccine beats tolerance in cirrhotic COVID-19 patients
06 Nov 2022
Tuberculosis doubles risk of death in patients on ART
Tuberculosis doubles risk of death in patients on ART
06 Nov 2022

Coinfection of tuberculosis (TB) among people with HIV initiating antiretroviral therapy (ART) aggravates the risk of death, a recent study has found.

Tuberculosis doubles risk of death in patients on ART
06 Nov 2022