News & Updates

FOLFOX/XELOX improves survival, response rate in CRC patients with DDR-mutated tumour

13 Feb 2021

Mutations affecting DNA damage response (DDR) are present in 22 percent of patients with metastatic colorectal cancer (CRC), reports a study. Initial treatment with fluoropyrimidine with oxaliplatin (FOLFOX/XELOX) improves overall survival in this population and is associated with a numerically higher response rate than fluoropyrimidine with irinotecan (FOLFIRI).

FOLFOX/XELOX improves survival, response rate in CRC patients with DDR-mutated tumour

13 Feb 2021

Tacrolimus ointment helps restore pigment in facial vitiligo

12 Feb 2021 by

Applying topical tacrolimus 0.1% twice daily for 6 months proves effective in the treatment of adult patients with facial vitiligo, as shown in a study.

Tacrolimus ointment helps restore pigment in facial vitiligo

12 Feb 2021

High-dose adrenomedullin effective against steroid-resistant ulcerative colitis

11 Feb 2021

Adults with steroid-resistant ulcerative colitis may fare well with the vasodilatory peptide adrenomedullin at a high dose, which has been shown to induce complete remission within 8 weeks in a phase IIa trial.

High-dose adrenomedullin effective against steroid-resistant ulcerative colitis

11 Feb 2021

Antidepressants offer slight benefit for back pain, osteoarthritis

11 Feb 2021 by

Serotonin-noradrenaline reuptake inhibitors (SNRIs) provide a small influence on pain and disability scores and appear to have no clinically significant benefit for back pain, as shown by moderate certainty evidence from a systematic review and meta-analysis. However, such effect cannot be ignored for osteoarthritis (OA). Moreover, tricyclic antidepressants (TCAs) and SNRIs may benefit patients with sciatica, but the certainty of evidence is low to very low.

Antidepressants offer slight benefit for back pain, osteoarthritis

11 Feb 2021

Repeated ketamine infusions ease PTSD symptoms

11 Feb 2021 by

Repeated ketamine administration is effective in the reduction of symptom severity in individuals with chronic post-traumatic stress disorder (PTSD), suggests a study.

Repeated ketamine infusions ease PTSD symptoms

11 Feb 2021

IV golimumab works in kids with polyarticular-course juvenile idiopathic arthritis

11 Feb 2021

Body surface area-based dosing of intravenous (IV) golimumab appears safe and provides pharmacokinetic exposure in paediatric patients with active polyarticular-course juvenile idiopathic arthritis similar to that found in adults with rheumatoid arthritis, according to the results of an open-label study.

IV golimumab works in kids with polyarticular-course juvenile idiopathic arthritis

11 Feb 2021

Ivermectin useful for treating mild COVID-19

11 Feb 2021

A 5-day course of the Food and Drug Administration-approved antiparasitic agent ivermectin appears safe and effective in the treatment of adult patients with early-onset mild COVID-19, a study has reported.

Ivermectin useful for treating mild COVID-19

11 Feb 2021

Early tocilizumab treatment in ICU tied to lower COVID-19 mortality

10 Feb 2021 by

Critically ill patients who received tocilizumab within 2 days of admission to the intensive care unit (ICU) for COVID-19 had a lower risk of mortality than those not treated with tocilizumab, according to a recent study.

Early tocilizumab treatment in ICU tied to lower COVID-19 mortality

10 Feb 2021

Major drug–drug Interactions occur in hospitalized solid tumour cancer patients

10 Feb 2021

A clinical pharmacy service that provides relevant pharmacotherapy consultations may be beneficial to hospitalized solid tumour cancer patients to prevent potentially serious concerns caused by moderate or major drug–drug interactions, suggests a recent study.

Major drug–drug Interactions occur in hospitalized solid tumour cancer patients

10 Feb 2021

Broad-spectrum antibiotic effective against chronic endometriosis

10 Feb 2021

A two-week course of broad-spectrum oral antibiotic therapy helps resolve chronic endometritis in about 90 percent of cases, although it is unclear whether this beneficial effect translates to improved pregnancy outcomes, according to a study.

Broad-spectrum antibiotic effective against chronic endometriosis

10 Feb 2021

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FOLFOX/XELOX improves survival, response rate in CRC patients with DDR-mutated tumour

FOLFOX/XELOX improves survival, response rate in CRC patients with DDR-mutated tumour

Tacrolimus ointment helps restore pigment in facial vitiligo

Tacrolimus ointment helps restore pigment in facial vitiligo

High-dose adrenomedullin effective against steroid-resistant ulcerative colitis

High-dose adrenomedullin effective against steroid-resistant ulcerative colitis

Antidepressants offer slight benefit for back pain, osteoarthritis

Antidepressants offer slight benefit for back pain, osteoarthritis

Repeated ketamine infusions ease PTSD symptoms

Repeated ketamine infusions ease PTSD symptoms

IV golimumab works in kids with polyarticular-course juvenile idiopathic arthritis

IV golimumab works in kids with polyarticular-course juvenile idiopathic arthritis

Ivermectin useful for treating mild COVID-19

Ivermectin useful for treating mild COVID-19

Early tocilizumab treatment in ICU tied to lower COVID-19 mortality

Early tocilizumab treatment in ICU tied to lower COVID-19 mortality

Major drug–drug Interactions occur in hospitalized solid tumour cancer patients

Major drug–drug Interactions occur in hospitalized solid tumour cancer patients

Broad-spectrum antibiotic effective against chronic endometriosis

Broad-spectrum antibiotic effective against chronic endometriosis