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Smoking during pregnancy ups hypertension risk in offspring
Children exposed to maternal smoking during pregnancy have higher systolic blood pressure (SBP) and are at a heightened risk of hypertension, a recent study has found.
Smoking during pregnancy ups hypertension risk in offspring
20 Oct 2022
Prexasertib works in select patients with recurrent ovarian cancer
CHK1 inhibition with prexasertib appears to have durable activity in some patients with recurrent ovarian cancer regardless of clinical characteristics, BRCA status, or prior therapies, according to the results of a phase II trial.
Prexasertib works in select patients with recurrent ovarian cancer
14 Oct 2022
Sacituzumab govitecan confers OS benefit for HR+/HER2– metastatic breast cancer
In the second interim overall survival (OS) analysis of the phase III TROPiCS-02 study, sacituzumab govitecan (SG) – a first-in-class Trop-2*-directed antibody-drug conjugate approved for triple-negative metastatic breast cancer (mBC) with ≥2 prior therapies (≥1 in the metastatic setting) – conferred an OS benefit for pretreated HR+/HER2– mBC, compared with treatment of physician’s choice (TPC**).