News & Updates

Single tremelimumab priming dose exhibits acceptable safety for advanced HCC

14 Sep 2020 by

The novel combination regimen comprising the immune checkpoint inhibitors (ICIs) durvalumab (anti-PD-L1) and tremelimumab (anti-CTLA-4) showed a favourable safety profile and clinical activity for advanced hepatocellular carcinoma (HCC), according to detailed safety data presented at ESMO GI 2020.

Single tremelimumab priming dose exhibits acceptable safety for advanced HCC

14 Sep 2020

Oestradiol-progesterone combo cleared of abnormal mammogram risk

14 Sep 2020

Treatment with the oral combination of 17β-oestradiol and progesterone in postmenopausal women does not appear to be related to abnormal mammograms, and the incidence of breast tenderness is low as compared with the rates reported in other hormone therapy studies, according to data from the phase III trial REPLENISH.

Oestradiol-progesterone combo cleared of abnormal mammogram risk

14 Sep 2020

Rhythm vs rate control in AF: A win finally?

12 Sep 2020 by

Early initiation of rhythm-control therapy led to a significantly reduced risk of major adverse cardiovascular (CV) outcomes compared with usual care (typically rate control) in patients with newly diagnosed atrial fibrillation (AF) at risk of stroke, reveals the EAST-AFNET 4* trial presented at ESC 2020.

Rhythm vs rate control in AF: A win finally?

12 Sep 2020

Vedolizumab effective against ulcerative colitis in Asians

11 Sep 2020 by

Ulcerative colitis patients from Asian countries fare as well as their peers from other parts of the world on vedolizumab, according to an exploratory analysis of the GEMINI-1 study.

Vedolizumab effective against ulcerative colitis in Asians

11 Sep 2020

Flu vaccination during pregnancy does not up autism risk in offspring

11 Sep 2020

Maternal influenza A/H1N1 immunization during pregnancy is not associated with an increased risk for autism spectrum disorder (ASD) in the offspring, results of a large cohort study have shown.

Flu vaccination during pregnancy does not up autism risk in offspring

11 Sep 2020

Prasugrel de-escalation may benefit ACS patients after PCI

11 Sep 2020 by

A prasugrel de-escalation strategy significantly reduced the risk of NACE* and bleeding events in patients with ACS** after PCI*** compared with the conventional strategy, results of the HOST-REDUCE-POLYTECH-ACS# trial have shown.

Prasugrel de-escalation may benefit ACS patients after PCI

11 Sep 2020

Add-on oral corticosteroid of little benefit in persistent asthma

11 Sep 2020

A short-term course of oral corticosteroid medication does not appear to improve disease control in patients with moderate to severe persistent asthma initiating treatment with inhaled corticosteroid-and-long-acting beta agonist (ICS-LABA).

Add-on oral corticosteroid of little benefit in persistent asthma

11 Sep 2020

Calcium channel blockers may raise prostate cancer risk

11 Sep 2020

Men who use calcium channel blockers (CCBs) are at risk of developing prostate cancer, and the risk increases with the duration of CCB exposure, according to the results of a systematic review and meta-analysis.

Calcium channel blockers may raise prostate cancer risk

11 Sep 2020

Aldafermin significantly reduces liver fat in patients with NASH

11 Sep 2020 by

Treatment with an FGF19 analogue aldafermin, previously known as NGM282, led to a significantly reduced liver fat content (LFC) in patients with nonalcoholic steatohepatitis (NASH), according to a study presented at ILC 2020.

Aldafermin significantly reduces liver fat in patients with NASH

11 Sep 2020

Switch from TDF to TAF does not affect viral suppression in chronic HBV

10 Sep 2020 by

In virologically suppressed patients with chronic hepatitis B virus (HBV) infection, switching from tenofovir disoproxil fumarate (TDF) to tenofovir alafenamide (TAF) did not affect their rates of viral suppression, according to the final 96-week analysis of a phase III study.

Switch from TDF to TAF does not affect viral suppression in chronic HBV

10 Sep 2020

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Single tremelimumab priming dose exhibits acceptable safety for advanced HCC

Single tremelimumab priming dose exhibits acceptable safety for advanced HCC

Oestradiol-progesterone combo cleared of abnormal mammogram risk

Oestradiol-progesterone combo cleared of abnormal mammogram risk

Rhythm vs rate control in AF: A win finally?

Rhythm vs rate control in AF: A win finally?

Vedolizumab effective against ulcerative colitis in Asians

Vedolizumab effective against ulcerative colitis in Asians

Flu vaccination during pregnancy does not up autism risk in offspring

Flu vaccination during pregnancy does not up autism risk in offspring

Prasugrel de-escalation may benefit ACS patients after PCI

Prasugrel de-escalation may benefit ACS patients after PCI

Add-on oral corticosteroid of little benefit in persistent asthma

Add-on oral corticosteroid of little benefit in persistent asthma

Calcium channel blockers may raise prostate cancer risk

Calcium channel blockers may raise prostate cancer risk

Aldafermin significantly reduces liver fat in patients with NASH

Aldafermin significantly reduces liver fat in patients with NASH

Switch from TDF to TAF does not affect viral suppression in chronic HBV

Switch from TDF to TAF does not affect viral suppression in chronic HBV