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Add-on pembrolizumab–tocilizumab combo reduces hospitalization period in severe COVID-19
In the treatment of patients with severe COVID-19, adding the combination of pembrolizumab plus tocilizumab to standard of care (SOC) appears to result in higher and faster discharge from the hospital without sequelae, as shown in the proof-of-concept phase II COPERNICO trial.
Add-on pembrolizumab–tocilizumab combo reduces hospitalization period in severe COVID-19
29 Aug 2022Daytime, nocturnal hypertension pose risk of kidney replacement therapy in kids with CKD
Paediatric chronic kidney disease (CKD) patients with both daytime and nocturnal hypertension are at high risk of progressing to kidney replacement therapy, according to a study.
Daytime, nocturnal hypertension pose risk of kidney replacement therapy in kids with CKD
29 Aug 2022HK data: Long-acting injectable antipsychotics safer, more effective than oral antipsychotics for schizophrenia
Long-acting injectable antipsychotics (LAIAs) for schizophrenia are associated with lower risks of disease relapse, hospitalizations, and suicide attempts vs oral antipsychotics (OAs), without an increased risk of adverse events (AEs), according to a 16-year population-based self-controlled case series (SCCS) study by the University of Hong Kong.
HK data: Long-acting injectable antipsychotics safer, more effective than oral antipsychotics for schizophrenia
29 Aug 2022Gout, hyperuricaemia meds less common among diabetics on SGLT2is
Patients with type 2 diabetes mellitus (T2DM) taking sodium-glucose cotransporter 2 inhibitors (SGLT2is) are less likely to be prescribed antigout or antihyperuricaemic drugs, a recent study has found.
Gout, hyperuricaemia meds less common among diabetics on SGLT2is
28 Aug 2022FMT plus anti-inflammatory diet induces, preserves remission in UC
Patients with mild-to-moderate ulcerative colitis (UC) can achieve deep remission with multidonor faecal microbiota transplantation (FMT) and anti-inflammatory diet, according to an open-label trial. Furthermore, remission can be sustained with anti-inflammatory diet over 1 year.
FMT plus anti-inflammatory diet induces, preserves remission in UC
28 Aug 2022Dulaglutide safely controls glucose in T2D with CKD
In patients with type 2 diabetes (T2D) with chronic kidney disease (CKD), once-weekly dosage with dulaglutide achieves adequate glycaemic control along with a reduced decline in estimated glomerular filtration rate (eGFR), reports a recent study.
Dulaglutide safely controls glucose in T2D with CKD
28 Aug 2022Cervical cancer screening: Which HPV test to choose?
Adding a high-risk human papillomavirus (HPV) test to cytology may enhance detection of high-grade cervical intraepithelial neoplasia (CIN) in primary cervical cancer screening, with the Cobas 4800 and Hybrid Capture 2 (HC2) tests showing comparable clinical performance in high-risk HPV detection in Chinese women, according to a large study by the University of Hong Kong.