News &amp; Updates

ASCL1 a potential therapeutic target for treating Cushing’s disease

A recent study attempting to understand the pathogenesis of Cushing’s disease (CD) suggests the potential of achaete-scute complex homolog 1 (ASCL1), a pioneer transcription factor, as a therapeutic target for the treatment of CD.

ASCL1 a potential therapeutic target for treating Cushing’s disease

20 Aug 2022

Albumin, lymphocyte-to-monocyte ratio tied to tacrolimus response in ulcerative colitis

Concentrations of albumin and the ratio between lymphocyte and monocyte counts can predict failure of tacrolimus treatment in patients with ulcerative colitis, reports a recent study.

Albumin, lymphocyte-to-monocyte ratio tied to tacrolimus response in ulcerative colitis

Which factors predict relapse after antiviral therapy cessation in paediatric CHB?

Nearly one in three children with chronic hepatitis B (CHB) who discontinued their antiviral treatment has relapsed, a study has shown.

Which factors predict relapse after antiviral therapy cessation in paediatric CHB?

19 Aug 2022

Novel framework sets standard for ICU physiotherapists in Singapore

A recent study has identified 163 items of skills and knowledge that are necessary as a minimum standard for clinical practice for physiotherapists working in the intensive care unit (ICU) in Singapore.

Novel framework sets standard for ICU physiotherapists in Singapore

Hair loss common after COVID-19 infection

There appears to be an increased risk of hair loss – a phenomenon called telogen effluvium – after COVID-19 infection.

Hair loss common after COVID-19 infection

Bariatric surgery-induced improvement in HDL functionality tied to reduced inflammation

Individuals who undergo Roux-en-Y gastric bypass (RYGB) show improved high-density lipoprotein (HDL) functionality, which then contributes to a decrease in adipose tissue and systemic inflammation, reports a recent study.

Bariatric surgery-induced improvement in HDL functionality tied to reduced inflammation

Add-on dupilumab reduces OCS use in patients with steroid-dependent severe asthma

In patients with chronic dependence on oral corticosteroids (OCS) for severe asthma, long-term exposure to dupilumab supports sustained reduction in OCS dosage and improvement in clinical outcomes for up to 96 weeks, according to an analysis of the phase III LIBERTY ASTHMA TRAVERSE study.

Add-on dupilumab reduces OCS use in patients with steroid-dependent severe asthma

19 Aug 2022

SES, clinical factors trump brain MRI in predicting long-term neurodevelopment in CHD infants

In infants with congenital heart disease (CHD), the perioperative clinical course and socioeconomic status (SES) appear to be better predictors of long-term neurodevelopmental outcomes than conventional neonatal brain magnetic resonance imaging (MRI), a new study has found.

SES, clinical factors trump brain MRI in predicting long-term neurodevelopment in CHD infants

Probiotics, prebiotics, synbiotics boost metabolism in NAFLD