News & Updates

Novel drug GED-0301 for active Crohn's disease disappoints in phase III trial

08 Jun 2020 by

The novel drug mongersen (GED-0301), an oral antisense oligodeoxynucleotide directed against Smad7, has failed to demonstrate efficacy against placebo in active Crohn’s disease (CD), according to the results of a phase III trial.

Novel drug GED-0301 for active Crohn's disease disappoints in phase III trial

08 Jun 2020

Budesonide oral suspension improves endoscopic outcomes in eosinophilic oesophagitis

08 Jun 2020 by

Budesonide oral suspension (BOS), a liquid formulation of a topical corticosteroid, improved endoscopic outcomes in patients with eosinophilic oesophagitis (EoE), a phase III trial has shown.

Budesonide oral suspension improves endoscopic outcomes in eosinophilic oesophagitis

08 Jun 2020

Single-inhaler triple therapy combo improves FEV1 in patients with asthma

08 Jun 2020 by

Treatment with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI), a LAMA/ICS/LABA combination, significantly improves trough FEV₁* in symptomatic patients with inadequately controlled asthma compared with FF/VI only, according to the CAPTAIN** study presented at AAAAI 2020.

Single-inhaler triple therapy combo improves FEV1 in patients with asthma

08 Jun 2020

Yoga may reduce migraine frequency, intensity

05 Jun 2020 by

Adding a yoga regimen to medical therapy reduced the frequency and intensity of headaches among patients with episodic migraine, according to results of the CONTAIN trial.

Yoga may reduce migraine frequency, intensity

05 Jun 2020

Primary CV prevention with aspirin may be more harmful than beneficial in diabetics

05 Jun 2020

Using aspirin for the primary prevention of cardiovascular (CV) diseases appears to confer increased harm and lack of survival benefit, yielding a modest decrease in major adverse CV events but a concomitant elevation in major bleeding, according to a study.

Primary CV prevention with aspirin may be more harmful than beneficial in diabetics

05 Jun 2020

Paroxetine effective for intractable, persistent cough in cancer patients

05 Jun 2020

Paroxetine shows promise as an effective, off-label treatment for intractable and persistent cough in patients with advanced cancer, a study has shown.

Paroxetine effective for intractable, persistent cough in cancer patients

05 Jun 2020

Darunavir of no help in COVID-19

05 Jun 2020

Darunavir lacks potent in vitro antiviral activity against SARS-CoV-2 and is therefore not supported for use in the treatment of COVID-19, according to a recent study.

Darunavir of no help in COVID-19

05 Jun 2020

Fremanezumab does not raise CV concerns, even in high-risk migraine patients

04 Jun 2020 by

Patients using the CGRP* blocker fremanezumab for migraine treatment need not worry about cardiovascular (CV) safety of the drug, as pooled data from three phase III trials showed no safety signals for CV events with the treatment, even in those with a CV medical history.

Fremanezumab does not raise CV concerns, even in high-risk migraine patients

04 Jun 2020

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

04 Jun 2020

Use of metformin is effective in preventing hyperglycaemia in nondiabetic cancer patients exposed to high-dose prednisone-based chemotherapy, results of a randomized study have shown.

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

04 Jun 2020

Infection risk comparable between biologics, nonbiologics in children with psoriasis

04 Jun 2020

No substantial difference in infection risk is seen between biologics and nonbiologics among children with psoriasis, reveals a recent study. There is also no robust difference between systemic treatment and phototherapy.

Infection risk comparable between biologics, nonbiologics in children with psoriasis

04 Jun 2020

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Novel drug GED-0301 for active Crohn's disease disappoints in phase III trial

Novel drug GED-0301 for active Crohn's disease disappoints in phase III trial

Budesonide oral suspension improves endoscopic outcomes in eosinophilic oesophagitis

Budesonide oral suspension improves endoscopic outcomes in eosinophilic oesophagitis

Single-inhaler triple therapy combo improves FEV1 in patients with asthma

Single-inhaler triple therapy combo improves FEV1 in patients with asthma

Yoga may reduce migraine frequency, intensity

Yoga may reduce migraine frequency, intensity

Primary CV prevention with aspirin may be more harmful than beneficial in diabetics

Primary CV prevention with aspirin may be more harmful than beneficial in diabetics

Paroxetine effective for intractable, persistent cough in cancer patients

Paroxetine effective for intractable, persistent cough in cancer patients

Darunavir of no help in COVID-19

Darunavir of no help in COVID-19

Fremanezumab does not raise CV concerns, even in high-risk migraine patients

Fremanezumab does not raise CV concerns, even in high-risk migraine patients

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

Metformin prevents prednisone-induced hyperglycaemia in haematological cancers

Infection risk comparable between biologics, nonbiologics in children with psoriasis

Infection risk comparable between biologics, nonbiologics in children with psoriasis