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A topical ophthalmic suspension combination of povidone-iodine (PVP-I; 0.6%) and dexamethasone (DEX; 0.1%) appears to confer no clinical benefits to patients with bacterial conjunctivitis, according to the results of a phase III trial.
Use of furosemide plus salt supplement in addition to fluid restriction does not prove to be more effective than fluid restriction alone in correcting hyponatremia in patients with syndrome of inappropriate antidiuresis (SIAD), according to data from the EFFUSE-FLUID* trial.
Using the Fasting Algorithm for Singaporeans with Type 2 Diabetes (FAST) management tool improved glycaemic control among individuals with type 2 diabetes (T2D) who fasted during Ramadan, a recent study showed.
Clinicians vary as to how they manage drug–drug interactions (DDIs) with direct oral anticoagulants (DOACs) in clinical practice, with potentially substantial DDIs with DOACs still occurring despite computerized alerts, according to a study.
The addition of the anti-PD-1* monoclonal antibody pembrolizumab to platinum-based neoadjuvant chemotherapy (CT) led to a significant increase in the proportion of women with early triple-negative breast cancer (TNBC) who had a pathological complete response (pCR), the phase III KEYNOTE-522 trial has shown.
Antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs), appear to increase the risk of fractures in older adults, a recent study has shown.
Adding liraglutide to first-line lifestyle therapy led to a significantly reduced BMI standard-deviation score (BMI SDS*) among obese adolescents who failed to respond to lifestyle therapy alone, according to a study presented at ENDO 2020.