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Current treatment considerations for precision medicine: Bridging scientific data to clinical practice
Center for Integrated Oncology
University of Cologne, Germany
Precision medicine and tumour-agnostic approach are changing the landscape of non-small-cell lung cancer (NSCLC) and many other advanced solid tumours without satisfactory standard treatments. In an industry-sponsored meeting endorsed by the Hong Kong Society of Clinical Oncology, Professor Jürgen Wolf of the Center for Integrated Oncology, University of Cologne, Germany, lead investigator of an international phase II trial that led to the approval of capmatinib for advanced NSCLC harbouring MET exon 14 (METex14) skipping mutation, discussed the importance of panel molecular testing and targeted therapy in different solid tumours, focusing in particular on advanced NSCLC with actionable driver mutations, such as MET alterations.
Current treatment considerations for precision medicine: Bridging scientific data to clinical practice
08 Mar 2024Pulse vs nonpulse corticosteroid: Which is better against IPF?
Patients with acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF) who received a pulse dose of corticosteroids do not appear to have longer survival than those who received conventional nonpulse dose of corticosteroids, results of a study have shown.
Pulse vs nonpulse corticosteroid: Which is better against IPF?
07 Mar 2024Lipoprotein(a) predicts MACE in patients with or without ASCVD
Increased lipoprotein(a) (Lp[a]) appears predictive of long-term major adverse cardiovascular events (MACE) in people with and without baseline atherosclerotic cardiovascular disease (ASCVD), according to a recent study.
Lipoprotein(a) predicts MACE in patients with or without ASCVD
07 Mar 2024Needle-free epinephrine an alternative for anaphylaxis?
In a study presented at AAAAI 2024, epinephrine in preservative-free, nasal powder formulations demonstrated superior stability and comparable plasma exposure to the EpiPen® autoinjector, thus providing a less-invasive treatment option for severe allergic reactions including anaphylaxis.