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Genital tract infections not a risk factor for cytologic abnormalities regardless of HPV infection status
Neither vulvovaginal candidiasis nor bacterial vaginosis is associated with increased incidence of cervical cytologic abnormalities among women with or without human papillomavirus (HPV) infection, according to a study. Bacterial vaginosis may even have a protective effect against cytologic abnormalities among women with HPV coinfection.
Genital tract infections not a risk factor for cytologic abnormalities regardless of HPV infection status
11 Feb 2023
Novel KRAS G12C inhibitor shows promising antitumour activity in mutated pancreatic cancer
The investigational KRAS G12C inhibitor sotorasib appears to be active against previously treated KRAS p.G12C–mutated advanced pancreatic cancer while having an acceptable safety profile, according to the results of a phase I/II trial.
Novel KRAS G12C inhibitor shows promising antitumour activity in mutated pancreatic cancer
11 Feb 2023
Alcohol drinking blamed for rise in colorectal cancer cases among young adults
Consumption of alcohol appears to be a risk factor for early-onset colorectal cancer and has driven an increase in the incidence of colorectal cancer among young adults, as shown in a study.
Alcohol drinking blamed for rise in colorectal cancer cases among young adults
10 Feb 2023
Mutational ctDNA analysis helps predict benefit of 2L ripretinib or sunitinib in GIST
Next-generation sequencing (NGS)–based analysis of circulating tumour DNA (ctDNA) helps predict benefit of second-line (2L) ripretinib or sunitinib therapy in patients with imatinib-resistant advanced gastrointestinal stromal tumours (GIST), an exploratory subanalysis of the INTRIGUE trial has shown.
Mutational ctDNA analysis helps predict benefit of 2L ripretinib or sunitinib in GIST
07 Feb 2023
Radiation therapy may raise colorectal cancer risk among Hodgkin's lymphoma survivors
Individuals who received radiation therapy for Hodgkin's lymphoma are at increased risk of colorectal cancer, as reported in a study.