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Sintilimab-IBI305-chemo improves PFS in EGFRm non-squamous NSCLC
The combination of the anti-PD-1 monoclonal antibody sintilimab with the bevacizumab biosimilar IBI305 and pemetrexed and cisplatin chemotherapy improved progression-free survival (PFS) in patients with EGFR*-mutated (EGFRm) non-squamous non-small-cell lung cancer (NSCLC), according to interim analysis results of the phase III ORIENT-31 trial from China.
Sintilimab-IBI305-chemo improves PFS in EGFRm non-squamous NSCLC
24 Dec 2021
Foetal brain unaffected by mild-to-moderate COVID-19 in pregnancy
Mild-to-moderate COVID-19 during pregnancy does not appear to affect the foetal brain, according to a prospective study presented at RSNA 2021.
Foetal brain unaffected by mild-to-moderate COVID-19 in pregnancy
20 Dec 2021
Extracorporeal CO2 removal safe, effective for acute exacerbation of COPD
Extracorporeal CO2 removal (ECCO2R) devices significantly improve pH and carbon dioxide arterial pressure (PaCO2) in patients with acute exacerbation of chronic obstructive pulmonary disease (ae-COPD) who had previously failed noninvasive ventilation (NIV), according to a recent study.
Extracorporeal CO2 removal safe, effective for acute exacerbation of COPD
20 Dec 2021
Early-life exposures to smoking, infection, abuse up risk of COPD in adulthood
Childhood respiratory disease, maltreatment, maternal smoking, and low birth weight are all associated with an increased risk of chronic obstructive pulmonary disease (COPD) in adulthood, a study has found.
Early-life exposures to smoking, infection, abuse up risk of COPD in adulthood
19 Dec 2021
No benefit from adding interferon beta-1a to remdesivir in COVID-19
Adding interferon beta-1a to remdesivir did not hasten time to recovery among adults hospitalized with COVID-19, according to results of the phase III ACTT*-3 trial.
