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Postpartum depression more common in pregnant women with rheumatic disease
Women of reproductive age with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), or rheumatoid arthritis (RA) are more likely to experience postpartum depression than those without any rheumatic disease (RD), according to a study.
Postpartum depression more common in pregnant women with rheumatic disease
19 Oct 2023
Ustekinumab biosimilar shows clinical similarity to reference drug for plaque psoriasis
A phase III study presented at EADV 2023 demonstrated the similarity between SB17, a human monoclonal antibody and proposed ustekinumab biosimilar, and reference ustekinumab for the treatment of moderate-to-severe plaque psoriasis.
Ustekinumab biosimilar shows clinical similarity to reference drug for plaque psoriasis
19 Oct 2023
Prednisolone ≥5 mg/day doubles risk of MACE in RA patients
In patients with rheumatoid arthritis (RA), use of systemic glucocorticoids (GC) is associated with a time- and dose-dependent increase in risk of major adverse cardiovascular events (MACE), a population-based real-world study has shown. On long-term follow-up, a prednisolone dose of ≥5 mg/day is associated with a doubled risk of MACE vs no GC use, and no safe duration of use is found for this daily GC dose.
Prednisolone ≥5 mg/day doubles risk of MACE in RA patients
17 Oct 2023
Otilimab for RA disappoints in ContRAst 3
In the treatment of select patients with rheumatoid arthritis (RA), otilimab is neither better than placebo nor noninferior to sarilumab in terms of the proportion of patients achieving an American College of Rheumatology ≥20 percent response (ACR20), according to the results of the phase III ContRAst 3 study.