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Fatty pancreas carries increased risk of diabetes mellitus
Individuals with fatty pancreas appear to be at heightened risk of developing subsequent diabetes mellitus, but not hypertension or dyslipidaemia, as suggested in a study.
Fatty pancreas carries increased risk of diabetes mellitus
14 Oct 2021KEYNOTE unlocks immunotherapy OS benefit in metastatic TNBC, effective in early disease
Triple-negative breast cancer (TNBC) is considered one of the highest-risk subtypes of breast cancer and has a dismal prognosis. However, immunotherapy survival benefits reported in KEYNOTE-522 and KEYNOTE-355 trials bring new hope for this indication. [Ann Oncol 2021;32:994-1004]
KEYNOTE unlocks immunotherapy OS benefit in metastatic TNBC, effective in early disease
14 Oct 2021Common, cheap osteoporosis drug promising for T2D
The osteoporosis drug alendronate halves the risk of developing type 2 diabetes (T2D) in a nationwide, retrospective, case-control study of nearly 700,000 patients from Denmark.
Common, cheap osteoporosis drug promising for T2D
14 Oct 2021Dapagliflozin improves symptoms, physical limitations in HFpEF
Patients with heart failure and preserved ejection fraction (HFpEF) treated with dapagliflozin experienced improvements in symptoms and physical limitations, according to results of the PRESERVED-HF study presented at HFSA 2021.
Dapagliflozin improves symptoms, physical limitations in HFpEF
13 Oct 2021Tocilizumab cuts COVID-19 mortality when administered during the early inflammatory stage
Tocilizumab does not seem to prevent the progression of the coronavirus disease 2019 (COVID-19) to critical disease but may still be valuable in severely ill patients when used during the early inflammatory stages, a recent study has found.
Tocilizumab cuts COVID-19 mortality when administered during the early inflammatory stage
13 Oct 2021Cilostazol makes good in DAPT for recurrent stroke prevention in high-risk patients
Dual antiplatelet therapy (DAPT) with cilostazol performs better than either aspirin or clopidogrel alone at reducing the risk of recurrent stroke or vascular events without increasing the incidence of bleeding for patients with ischaemic stroke and intracranial arterial stenosis, according to the results of the CSPS.com* trial.
Cilostazol makes good in DAPT for recurrent stroke prevention in high-risk patients
13 Oct 2021Wheat bran with RPS boosts serum SCFAs in obese people without improving health parameters
Consumption of wheat bran (WB) with reduced particle size (RPS) increases concentrations of fasting serum short-chain fatty acid (SCFA) in obese individuals, a study has shown. Such changes, however, do not appear to have beneficial effects on health parameters.