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Helmet-CPAP safely improves oxygenation in pregnant women with COVID-19 respiratory failure

27 Oct 2021 by

Administrating continuous positive airway pressure (CPAP) through a helmet (h-CPAP) device safely improves oxygenation in women with moderate-to-severe acute respiratory failure (ARF) due to the coronavirus disease 2019 (COVID-19), a recent study has found.

27 Oct 2021

Durvalumab + tremelimumab + chemo: A new first-line SoC for mNSCLC?

26 Oct 2021 by

The combination of durvalumab, tremelimumab, and chemotherapy in the first-line setting improved progression-free survival (PFS) and overall survival (OS) in patients with metastatic non-small-cell lung cancer (mNSCLC), according to results of the phase III POSEIDON trial.

26 Oct 2021

Baricitinib prevents death in critically ill COVID-19 patients

26 Oct 2021 by

The oral selective JAK1/2 inhibitor baricitinib significantly reduces the risk of death in critically ill COVID-19 patients who are on invasive mechanical ventilation (IMV) or ECMO*, when used in combination with standard care, according to the addendum study of the COV-BARRIER trial presented at IDWeek 2021.

26 Oct 2021

Molnupiravir pill: A game-changer in COVID-19?

24 Oct 2021 by

The investigational oral antiviral pill molnupiravir significantly slashed the risk of hospitalization or death by half in nonhospitalized adults with mild-to-moderate COVID-19, according to interim data from the phase III MOVe-OUT trial.

24 Oct 2021

Kids hard-hit by Delta; which ART performs best?

24 Oct 2021 by

That COVID-19 mostly spared children might be changing. The Delta variant has taken a severe, unthinkable toll on kids – at least in Arkansas, US, reports an expert at IDWeek 2021.

24 Oct 2021

Rapid antigen test: Don’t let perfect be the enemy of good

23 Oct 2021 by

While rapid antigen test is less sensitive than conventional nucleic acid amplification test (NAAT) such as RT-PCR* in detecting SARS-CoV-2 virus, “a test does not have to be perfect to be clinically useful,” said Professor Angela Caliendo during a session in IDWeek 2021 — echoing the maxim that perfect should not be the enemy of good in the pandemic era.

23 Oct 2021