Filters
Adding the anti-GM-CSF* receptor-α monoclonal antibody mavrilimumab to standard care (SC) improved clinical outcomes in patients with severe coronavirus disease 2019 (COVID-19) pneumonia and systemic hyperinflammation who were not under mechanical ventilation (MV), an Italian study has shown.
Substantial increases in cancer deaths may be anticipated due to delays in diagnosis during the coronavirus disease 2019 (COVID-19) pandemic, modelling studies in the UK have reported.
Use of cannabis or cannabinoids among patients with inflammatory bowel disease (IBD) does little to induce clinical remission or reduce inflammation, although it helps calm patient-reported symptoms and improve quality of life, a study has found.
Secondary hepatic dysfunction is prevalent in paediatric intensive care units (PICUs), a recent study has found. Risk factors include sepsis, hypoxia, and cardiovascular incidents.
When combined with the anti-PD-1 checkpoint inhibitor pembrolizumab, the investigational anti-HER2 monoclonal antibody margetuximab demonstrates synergistic antitumour activity against HER2 gastro-oesophageal adenocarcinoma, according to the results of a phase Ib–II trial.
