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Conservative excisional margin for small MIS tied to low recurrence
For small-sized melanoma in situ (MIS; <10 mm) on low-risk body sites, wide local excision (WLE) using a 5-mm margin was associated with a low rate of recurrence, a retrospective case series study has shown.

Tapinarof safe, efficacious for moderate-to-severe AD in children, adults
Treatment with tapinarof cream 1% once daily demonstrates significant efficacy with a favourable safety profile among adults and children with moderate-to-severe atopic dermatitis (AD), a study has shown.

Ongoing treatment required in severe patchy hair loss
For patients with severe alopecia areata who achieved meaningful hair regrowth with 1-year course of baricitinib, subsequent discontinuation appears to reverse treatment gains, highlighting the need for ongoing therapy.

Trans, saturated fat-heavy diets may trigger AD flares in Asians
High dietary consumption of trans fatty acids and saturated fatty acids appears to play some role in atopic dermatitis (AD) flare-ups among Chinese adults from Singapore and Malaysia, according to a large study.

Psoriasis control maintained with less frequent guselkumab dosing
A 16-week dosing interval for the IL-23 inhibitor guselkumab appears to sufficiently keep psoriasis controlled among patients who have achieved complete skin clearance shortly after starting standard treatment with the drug, according to the phase IIIb GUIDE clinical trial.



