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Add-on bispecific antibody may alter treatment landscape of G/GEJ cancer

12 Jun 2024 by

Adding the PD-1/CTLA-4 bispecific antibody cadonilimab to chemotherapy improves overall survival (OS) and progression-free survival (PFS) in individuals with untreated, HER2-negative, locally advanced or metastatic gastric or gastroesophageal junction (G/GEJ) cancer, including patients with PD-L1–low tumours, according to the interim results of the phase III COMPASSION-15 trial.

Add-on bispecific antibody may alter treatment landscape of G/GEJ cancer

12 Jun 2024

Hypertension a potential risk factor for endometrial cancer

12 Jun 2024

Hypertension contributes to a 14-percent increased risk of endometrial cancer, irrespective of diabetes, BMI, and reproductive factors, according to a study.

Hypertension a potential risk factor for endometrial cancer

12 Jun 2024

Pooled data support linaclotide for IBS-C irrespective of age

12 Jun 2024 by

Treatment with linaclotide significantly improved abdominal symptoms and the frequency of complete spontaneous bowel movements (CSBMs) among adult and elderly patients with irritable bowel syndrome with constipation (IBS-C), according to the pooled analysis of three phase III trials presented at DDW 2024.

Pooled data support linaclotide for IBS-C irrespective of age

12 Jun 2024

Bracing outcomes in teens with scoliosis do not differ with immediate vs gradual weaning protocol

11 Jun 2024 by

For teenagers with idiopathic scoliosis who wear a corrective brace, gradual removal of the device offers no significant advantage over immediate removal in terms of bracing outcomes and quality of life, according to the results of an open-label randomized clinical trial in Hong Kong.

Bracing outcomes in teens with scoliosis do not differ with immediate vs gradual weaning protocol

11 Jun 2024

Extreme temperature contributes to CV mortality

11 Jun 2024

Nonoptimal temperatures appear to be the cause of several cardiovascular (CV) deaths worldwide, according to a study.

Extreme temperature contributes to CV mortality

11 Jun 2024

Dual ACE inhibitor plus ARB therapy worsens kidney status in CKD

11 Jun 2024 by

Use of dual therapy with ACE inhibitors and ARBs tends to elevate the risk of renal outcomes in people with or without chronic kidney disease (CKD), reports a study presented at ERA 2024.

Dual ACE inhibitor plus ARB therapy worsens kidney status in CKD

11 Jun 2024

Dietitians can help improve outcomes in hypertensive adults

11 Jun 2024

Adults with elevated blood pressure (BP) may benefit from help provided by dietitians, suggests a study.

Dietitians can help improve outcomes in hypertensive adults

11 Jun 2024

Oral tacrolimus benefits haemodialysis patients with uraemic pruritus

11 Jun 2024 by

A study from Iran presented at ERA 2024 demonstrated the potential of oral tacrolimus to deliver an antipruritic effect in haemodialysis patients with uraemic pruritus.

Oral tacrolimus benefits haemodialysis patients with uraemic pruritus

11 Jun 2024

Mediterranean diet may lower death risk in women

11 Jun 2024

Higher adherence to the Mediterranean diet confers a 23-percent reduction in the risk of all-cause mortality, a benefit that may be partially explained by potential mediation by several cardiometabolic factors, according to a study.

Mediterranean diet may lower death risk in women

11 Jun 2024

One-fifth of people attempting suicide have no prior mental disorders

11 Jun 2024 by

One in five individuals who attempt suicide do not have a history of psychiatric disorders, a cross-sectional study has shown.

One-fifth of people attempting suicide have no prior mental disorders

11 Jun 2024

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Add-on bispecific antibody may alter treatment landscape of G/GEJ cancer

Add-on bispecific antibody may alter treatment landscape of G/GEJ cancer

Hypertension a potential risk factor for endometrial cancer

Hypertension a potential risk factor for endometrial cancer

Pooled data support linaclotide for IBS-C irrespective of age

Pooled data support linaclotide for IBS-C irrespective of age

Bracing outcomes in teens with scoliosis do not differ with immediate vs gradual weaning protocol

Bracing outcomes in teens with scoliosis do not differ with immediate vs gradual weaning protocol

Extreme temperature contributes to CV mortality

Extreme temperature contributes to CV mortality

Dual ACE inhibitor plus ARB therapy worsens kidney status in CKD

Dual ACE inhibitor plus ARB therapy worsens kidney status in CKD

Dietitians can help improve outcomes in hypertensive adults

Dietitians can help improve outcomes in hypertensive adults

Oral tacrolimus benefits haemodialysis patients with uraemic pruritus

Oral tacrolimus benefits haemodialysis patients with uraemic pruritus

Mediterranean diet may lower death risk in women

Mediterranean diet may lower death risk in women

One-fifth of people attempting suicide have no prior mental disorders

One-fifth of people attempting suicide have no prior mental disorders