News & Updates

In the first-line treatment of patients with microsatellite instability-high or mismatch repair-deficient (MSI-H/dMMR) metastatic colorectal cancer (CRC), dual immunotherapy using a combination of nivolumab and ipilimumab delivers a statistically significant and clinically meaningful improvement in progression-free survival (PFS) compared with chemotherapy, according to the CheckMate 8HW trial presented at ASCO GI 2024.

In patients who have had a first attack of pericarditis with evidence of myocardial involvement, treatment with colchicine is safe and helps reduce the risk of recurrence, according to a study.

Among Asian patients with systemic lupus erythematosus (SLE), those who are younger, male, from ethnic minority backgrounds, and have suboptimal disease control at time of vaccination are at increased risk of flares following mRNA COVID-19 vaccination.

Administration of oxathridine, a first-in-class histamine-3 receptor partial agonist, results in some serious adverse events (AEs), including orthostatic hypotension and pseudohallucinations in healthy male volunteers, results of a study have shown.

In the treatment of uncomplicated gram-negative bacteraemia, switching to oral antibiotics within 4 days appears to be effective, with the all-cause mortality risk comparable to that of continued intravenous (IV) antibiotic treatment, according to a study.