News & Updates

In patients with haemophilia A (PwHA) or B (PwHB) with inhibitors, annualized bleeding rate (ABR) was lower with daily subcutaneous (SC) concizumab prophylaxis than with on-demand treatment, findings from the phase IIIa explorer7 trial have shown.

Among patients receiving hydroxychloroquine for systemic lupus erythematosus (SLE), severe nonadherence to medication poses increased risks of SLE flare in the following year, early damage, and 5-year mortality, according to data from the SLICC* Inception Cohort.

For patients undergoing peritoneal dialysis, parathyroidectomy yields bigger increases in the bone mineral density (BMD) of lumbar spine and femoral neck as well as decreases in osteopenia/osteoporosis, according to a study.

For older adults with chronic kidney disease (CKD) who are initiating a disease-modifying antirheumatic drug (DMARD), low-dose methotrexate appears to be associated with a heightened 90-day risk of serious adverse events compared with hydroxychloroquine, as shown in a study.

A history of vascular disease appears to contribute to worse long-term outcomes in patients with atrial fibrillation (AF), but treatment with oral anticoagulation (OAC) helps, suggests a recent study.

The risk of colectomy in paediatric onset ulcerative colitis (UC) has significantly decreased at the population level along with an increase in the use of immunosuppressants and antitumour necrosis factor (anti-TNF), reports a study.