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Weight trajectories across reproductive years up risk of adverse pregnancy outcomes

23 Jul 2024

Weight gains prior to and between pregnancies appear to increase the risk of adverse pregnancy outcomes (APOs), reports a study. A longer period of weight gain shows the most robust association with an increased risk of APOs.

Weight trajectories across reproductive years up risk of adverse pregnancy outcomes

23 Jul 2024

Omaveloxolone slows neurological progression in earlier-onset Friedreich’s ataxia

22 Jul 2024 by

The treatment effect of omaveloxolone in halting progression, based on change in mFARS score, is particularly pronounced in individuals with Friedreich's ataxia who had disease onset at ≤15 years of age, suggests a post hoc subgroup analysis of MOXIe Part 2 presented at EAN 2024.

Omaveloxolone slows neurological progression in earlier-onset Friedreich’s ataxia

22 Jul 2024

Benralizumab facilitates complete withdrawal of OGCs more than mepolizumab in EGPA

22 Jul 2024 by

Benralizumab offers more sustained and earlier elimination of oral GCs vs mepolizumab in patients with relapsing or refractory EGPA, suggests a post hoc analysis of the MANDARA study presented at EULAR 2024

Benralizumab facilitates complete withdrawal of OGCs more than mepolizumab in EGPA

22 Jul 2024

Can rosuvastatin protect against chemo-induced cardiotoxicity in HER2+ breast cancer?

22 Jul 2024 by

Use of rosuvastatin is associated with a significantly lower decline in left ventricular ejection fraction (LVEF) and lower serum levels of cardiotoxicity-associated biomarkers in newly diagnosed HER2-positive breast cancer patients treated with anthracycline-based chemotherapy followed by trastuzumab, according to the results of a prospective, randomized, controlled, parallel study.

Can rosuvastatin protect against chemo-induced cardiotoxicity in HER2+ breast cancer?

22 Jul 2024

Over-the-counter supplement touted for improving walking distance in PAD

21 Jul 2024 by

Nicotinamide riboside supplements show a signal of benefit for helping patients with lower extremity peripheral arterial disease (PAD) walk more

Over-the-counter supplement touted for improving walking distance in PAD

21 Jul 2024

Type 1 diabetes linked to arrhythmia in Mendelian analysis

21 Jul 2024

Individuals with type 1 diabetes (T1D) are at heightened risk or arrythmia, with a causal relationship between the two medical conditions demonstrated in a two-sample Mendelian randomization (MR) study.

Type 1 diabetes linked to arrhythmia in Mendelian analysis

21 Jul 2024

Osteosarcopenia found in CT scans predicts higher mortality after TAVR in older adults

21 Jul 2024

Detecting osteosarcopenia in older adults using CT scans appears to be useful for identifying those with frailty, who may have a threefold increased risk of mortality following transcatheter aortic valve replacement (TAVR), according to a study.

Osteosarcopenia found in CT scans predicts higher mortality after TAVR in older adults

21 Jul 2024

High physical activity volume won’t worsen heart disease marker

20 Jul 2024

High and very high volumes of leisure-time aerobic physical activity do not appear to contribute to coronary artery calcium (CAC) progression over time, according to a study.

High physical activity volume won’t worsen heart disease marker

20 Jul 2024

Dual direct-current cardioversion improves atrial fibrillation conversion rates in obesity

19 Jul 2024

In patients with obesity undergoing electrical cardioversion for atrial fibrillation (AF), dual direct-current cardioversion (DCCV) appears to be more effective at converting AF into sinus rhythm compared with single DCCV, as reported in a study.

Dual direct-current cardioversion improves atrial fibrillation conversion rates in obesity

19 Jul 2024

Sirolimus-eluting PTA balloons keep most complex infrainguinal lesions CD-TLR–free for a year

19 Jul 2024 by

The use of a sirolimus-eluting balloon maintains freedom from clinically driven TLR at 1 year in nearly 3 out of 4 long, complex infrainguinal lesions, as shown in the PRISTINE registry of patients in Singapore with CLTI

Sirolimus-eluting PTA balloons keep most complex infrainguinal lesions CD-TLR–free for a year

19 Jul 2024

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Weight trajectories across reproductive years up risk of adverse pregnancy outcomes

Weight trajectories across reproductive years up risk of adverse pregnancy outcomes

Omaveloxolone slows neurological progression in earlier-onset Friedreich’s ataxia

Omaveloxolone slows neurological progression in earlier-onset Friedreich’s ataxia

Benralizumab facilitates complete withdrawal of OGCs more than mepolizumab in EGPA

Benralizumab facilitates complete withdrawal of OGCs more than mepolizumab in EGPA

Can rosuvastatin protect against chemo-induced cardiotoxicity in HER2+ breast cancer?

Can rosuvastatin protect against chemo-induced cardiotoxicity in HER2+ breast cancer?

Over-the-counter supplement touted for improving walking distance in PAD

Over-the-counter supplement touted for improving walking distance in PAD

Type 1 diabetes linked to arrhythmia in Mendelian analysis

Type 1 diabetes linked to arrhythmia in Mendelian analysis

Osteosarcopenia found in CT scans predicts higher mortality after TAVR in older adults

Osteosarcopenia found in CT scans predicts higher mortality after TAVR in older adults

High physical activity volume won’t worsen heart disease marker

High physical activity volume won’t worsen heart disease marker

Dual direct-current cardioversion improves atrial fibrillation conversion rates in obesity

Dual direct-current cardioversion improves atrial fibrillation conversion rates in obesity

Sirolimus-eluting PTA balloons keep most complex infrainguinal lesions CD-TLR–free for a year

Sirolimus-eluting PTA balloons keep most complex infrainguinal lesions CD-TLR–free for a year