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Empagliflozin improves outcomes in HFpEF patients regardless of age

Empagliflozin improves outcomes in HFpEF patients regardless of age

06 Jul 2022 byStephen Padilla

Treatment with empagliflozin results in a reduction in heart failure (HF) risk and renal outcomes and in better health-related quality of life (HRQoL) among patients with chronic HF with preserved ejection fraction (HFpEF), a study has shown. In addition, the study drug is well tolerated by older patients.

Empagliflozin improves outcomes in HFpEF patients regardless of age

06 Jul 2022
Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

06 Jul 2022

Children with ulcerative colitis seem to respond well to vedolizumab in the first-line setting, inducing remission without increasing the risk of adverse events, according to a small study.

Vedolizumab appears safe, effective in first-line treatment of ulcerative colitis in children

06 Jul 2022
PARG inhibition slows HCC progression, boosts efficacy of immune checkpoint therapy

PARG inhibition slows HCC progression, boosts efficacy of immune checkpoint therapy

05 Jul 2022

In hepatocellular carcinoma (HCC), poly(ADP-ribose) glycohydrolase (PARG) may serve as an oncogene by modulating PARG/DDB1/c-Myc signaling and be used as a biomarker to identify HCC patients who may derive benefit from anti-PD-1 treatment, suggests a study.

PARG inhibition slows HCC progression, boosts efficacy of immune checkpoint therapy

05 Jul 2022
Concurrent DOAC, tamoxifen use poses no elevated bleeding risk

Concurrent DOAC, tamoxifen use poses no elevated bleeding risk

05 Jul 2022

In breast cancer patients receiving direct oral anticoagulants (DOACs), tamoxifen is safe to use and does not increase the risk of haemorrhage as compared with concurrent use of an aromatase inhibitor (AI), a study has found.

Concurrent DOAC, tamoxifen use poses no elevated bleeding risk

05 Jul 2022