News & Updates

Female patients nonvalvular atrial fibrillation (AF) are less often prescribed guideline-recommended oral anticoagulation at the emergency department (ED), which in turn contributes to an increased stroke risk at 1 year regardless of discharge status, a study has found.

Among patients on concomitant treatment with direct oral anticoagulants (DOACs) and dronedarone, no difference is seen in survival free from the composite endpoint (ie, clinically relevant bleeding, thromboembolic event, and all-cause death) and from clinically relevant bleeding between groups of coadministration, according to a study.

Treatment with statins is effective at lowering cardiovascular disease risk, with the protective effect seemingly stronger in women than in men, according to a study. However, high-intensity regimens confer only minimal additional benefit in both sexes.

Use of phosphodiesterase type 5 (PDE5) inhibitors has increased 20-fold from 2000 to 2018, according to a study of Danish patients with ischaemic heart disease (IHD) who were taking nitrates. In addition, no statistically significant association has been observed between concomitant use of PDE5 inhibitors and cardiovascular adverse events.

The human monoclonal IgG4 antibody dupilumab effectively treats prurigo nodularis (PN), including itching and skin lesions, weeks after treatment in the phase III randomized, double-blind, LIBERTY-PN PRIME2 trial. Hopefully, this brings relief to patients suffering from uncontrolled PN.