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HK data: Long-acting injectable antipsychotics safer, more effective than oral antipsychotics for schizophrenia
Long-acting injectable antipsychotics (LAIAs) for schizophrenia are associated with lower risks of disease relapse, hospitalizations, and suicide attempts vs oral antipsychotics (OAs), without an increased risk of adverse events (AEs), according to a 16-year population-based self-controlled case series (SCCS) study by the University of Hong Kong.

Pimavanserin trumps atypical antipsychotics in preventing death in Parkinson’s disease patients
Use of pimavanserin appears to be more effective than atypical antipsychotic agents in reducing mortality among Parkinson’s disease patients during the first 180 days of treatment, reveals a study. However, such benefit is seen only in community-dwelling patients and not in nursing home residents.

Use of antipsychotics, but not opioids, drops in nursing home residents with dementia
Prescription of antipsychotic and anxiolytic medications has decreased among residents with dementia in Veterans Health Administration (VHA) nursing homes, but overall prescribing of other psychotropic and opioid agents has increased, reports a study.

Relapse prevention interventions effective in MDD
In patients with remitted major depressive disorder (MDD), the use of psychological relapse prevention interventions, whether as a standalone or in combination with medication, effectively reduces the risk of relapse/recurrence, according to a recent meta-analysis.

Meta-analysis: “Sunshine vitamin” may brighten mood
Vitamin D is known for its role in bone ossification, and most of this vitamin is made when skin is exposed to sunlight. Recently, a meta-analysis has reported that supplemental vitamin D can help alleviate depressive symptoms in adults.

Labour epidural analgesia not a risk factor for offspring ASD, ADHD
Children born to mothers who were exposed to labour epidural analgesia do not appear to be at greater risk of autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD), according to a study.



